Clinico-microbiological profile and visual outcomes of post-traumatic endophthalmitis at a tertiary eye care center in South India

Vedantham, Vasumathy; Nirmalan, Praveen K; Ramasamy, Kim; Prakash, Karthik; Namperumalsamy, P

doi:10.4103/0301-4738.21607

Cited by 36 publications

(25 citation statements)

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“…2,6,20,21 This seems to be because of technical issues rather than sterile endophthalmitis. The most common culture results identified the presence of Gram-negative bacteria.…”

Section: Discussionmentioning

confidence: 89%

Posttraumatic Endophthalmitis

Faghihi¹,

Hajizadeh²,

Esfahani³

et al. 2012

Retina

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Posttraumatic endophthalmitis is more likely among patients with open-globe injury that are needle related and among those who have intraocular foreign bodies, traumatic lens rupture, smaller wounds, or wounds exclusively in the cornea. Lower ocular trauma scores in this group of patients with penetrating trauma indicated a greater risk of poor visual prognosis. Therefore, it is suggested that necessary measures and immediate treatment be undertaken in high-risk patients.

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“…2,6,20,21 This seems to be because of technical issues rather than sterile endophthalmitis. The most common culture results identified the presence of Gram-negative bacteria.…”

Section: Discussionmentioning

confidence: 89%

Posttraumatic Endophthalmitis

Faghihi¹,

Hajizadeh²,

Esfahani³

et al. 2012

Retina

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“…Consistent with other reports, gram-positive organisms were the predominant pathogens, and Staphylococcus species remained to be the most common infectious organisms. 1,[9][10][11][12][13][14] The differences between this and previous reports included the present observation of a larger proportion of fungi than gram-negative organisms (18.4 vs.16.6) and the decrease in gram-negative organisms from 32% to 11% (P = 0.019) and increase in the percentage of gram-positive bacteria from 49% to 73% (P = 0.174) over a 10-year period, which disagree with the findings of a study by Gentile et al 15 The reasons for this difference remain unclear. Factors influencing variation between multiple reported studies include the period in time analyzed, prevalence of predisposing illnesses, geographic factors in organism incidence, urban versus rural settings, ethnicity, outpatient versus inpatient populations especially those in tertiary care centers, and climatic factors.…”

Section: Discussionmentioning

confidence: 98%

Microbiological Isolates and Antibiotic Susceptibilities: A 10-Year Review of Culture-Proven Endophthalmitis Cases

Liu

et al. 2016

Current Eye Research

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“…Gram-positive, coagulase-negative Staphylococcus is the predominant organism in most series including miscellaneous [1], postoperative [2], and posttraumatic endophthalmitis [3], also in our series (26.4%). Normal conjunctival flora is one of the main sources of infection [4].…”

Section: Discussionmentioning

confidence: 99%

Isolates and Antibiotic Sensitivity of Eighty Culture-Proven Endophthalmitis Cases from Istanbul

Eser¹,

Kapran²,

Altan³

et al. 2008

Ophthalmologica

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Purpose: To investigate the spectrum of organisms causing endophthalmitis and their sensitivity to commonly used antimicrobial agents. Methods: Medical records of 80 consecutive patients treated at Beyoglu Eye Hospital for endophthalmitis from January 2001 to April 2006 were reviewed. Specimens were obtained from either the vitreous (93%, 81/87) or anterior chamber (7%, 6/87) during pars plana vitrectomy or vitreous tap, and were inoculated into blood culture bottles. A Kirby-Bauer disk diffusion test was performed to determine antibiotic susceptibility. The outcome measures included isolates identified and antibiotic sensitivity of the specimens. Results: Fifty-six of 87 (64.4%) isolates were Gram-positive organisms, 29 (33.3%) were Gram-negative organisms, and 2 (2.3%) were fungi. The most common organism group identified was coagulase-negative staphylococci in 26.4% (23/87). While vancomycin was active against all Gram-positive isolates tested (100%), ceftazidime had the highest susceptibility rate (100%) for Gram-negative organisms isolated. Conclusions: Although coagulase-negative micrococci predominated in this series, a high isolation rate for Gram-negative organisms was obtained. High susceptibility rates for ofloxacin make it an alternative to ceftazidime and vancomycin in both Gram-negative- and Gram-positive-derived endophthalmitis, respectively. Studies with larger series and additional antibiotics are needed to confirm these findings.

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Clinico-microbiological profile and visual outcomes of post-traumatic endophthalmitis at a tertiary eye care center in South India

Cited by 36 publications

References 0 publications

Posttraumatic Endophthalmitis

Posttraumatic Endophthalmitis

Microbiological Isolates and Antibiotic Susceptibilities: A 10-Year Review of Culture-Proven Endophthalmitis Cases

Isolates and Antibiotic Sensitivity of Eighty Culture-Proven Endophthalmitis Cases from Istanbul

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