2021
DOI: 10.1136/bmjopen-2020-041854
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Clinicopathological analysis of 5146 eyelid tumours and tumour-like lesions in an eye centre in South China, 2000–2018: a retrospective cohort study

Abstract: ObjectivesTo describe the clinicopathological characteristics of patients with eyelid tumours and tumour-like lesions in South China, investigate possible factors affecting tumour constitution.DesignRetrospective cohort study.SettingAll patients diagnosed with eyelid tumours were included from a high-volume tertiary eye care centre from South China which caring for over 2000 patients per day. All biopsied specimens were reviewed by two senior pathologists and were classified according to the fourth edition of … Show more

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Cited by 19 publications
(12 citation statements)
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“…Prolonged exposure to sunlight seems to be an important predisposing factor of this predominance [57]. No preference of benign tumors in the upper eyelid was observed as described before [6,53]. Of seven patients with bilateral eyelid tumors in our study, six of them were xanthoma.…”
Section: Et Al [49]supporting
confidence: 65%
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“…Prolonged exposure to sunlight seems to be an important predisposing factor of this predominance [57]. No preference of benign tumors in the upper eyelid was observed as described before [6,53]. Of seven patients with bilateral eyelid tumors in our study, six of them were xanthoma.…”
Section: Et Al [49]supporting
confidence: 65%
“…The majority of eyelid tumors represent as benign proliferative ones. Skin tumors involve the eyelid region in up to 10% of cases, with BCCs being the most prevalent among Chinese population [6]. Various factors affecting the incidence of benign and malignant eyelid tumors, including race, geography, and genetics.…”
Section: Et Al [49]mentioning
confidence: 99%
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“…Sebaceous gland carcinoma (SGC) of the eyelid is a type of malignant epithelial tumor originating from sebaceous glands of the eyelid. SGC is the second most common malignant eyelid tumor in a number of Asian countries and ranks either third or fourth in various European countries (1,2). TNM staging, larger tumor diameter, recurrence, metastasis and perivascular invasion are clinical factors for poor prognosis (3)(4)(5), and patients with SGC are prone to recurrence and metastasis after surgery, which also results in poor prognosis (6).…”
Section: Introductionmentioning
confidence: 99%
“…It is known that predominantly diagnostics of pathological conditions of eyelids is based on clinical symptoms, ocular examination and the histopathologic findings [1]- [4]. In recent years, there has been an increase in interest in the development of noninvasive and innovative methods of eyelids' examination for the determination of early pathological features.…”
Section: Introductionmentioning
confidence: 99%