Clostridium Difficile Infection Complicated By Toxic Megacolon In Immunocompetent Patient

Abstract

Toxic megacolon can be a form of severe clinical course of the infection with Clostridium difficile (ICD), lifethreatening, requiring a particular course of treatment.

The role of gut fungi in Clostridioides difficile infection

“…CDI is directly related to the destruction of the microbiome after anti-biotherapy (especially fluoroquinolone, cephalosporin, clindamycin) [ 16 ]. The abundance of fungi and bacteria in the gut shows a clear negative correlation.…”