Clostridium difficile infection increases mortality risk in lung transplant recipients

HBV infection decreases risk of liver metastasis in patients with colorectal cancer: A cohort study

“…CDI also increases risk of death in SOT recipients. Early CDI (i.e., first episode of CDI less than 6 months after transplant) was found to be an independent risk factor for death among lung transplant recipients (HR 1.96, 95% confidence interval 1.14-3.36) [10].…”

“…The proportion of patients requiring colectomy is often observed to be higher in SOT recipients. Recent observational studies noted that approximately 3-4% of SOT recipients with CDI underwent colectomy, compared with less than 1% among the general hospitalized population [3,10,24]. CDI also increases risk of death in SOT recipients.…”

“…SOT recipients appear to be particularly vulnerable to adverse outcomes associated with CDI compared with other patient populations [10].…”

Clostridium difficile infection in solid organ transplant recipients

“…This change might be due to the emergence of the epidemic NAP1/BI/027 strain [23]; however, the impact of the emergence of the epidemic strain on severity of CDI among SOT recipients is not known. Recent observational studies noted that approximately 3-4% of SOT recipients with CDI underwent colectomy, compared with less than 1% among the general hospitalized population [3,10,24]. The proportion of patients requiring colectomy is often observed to be higher in SOT recipients.…”

“…Complicated CDI is more frequently observed in SOT recipients: up to 13% of SOT recipients with CDI develop fulminant colitis [9]. Early CDI (i.e., first episode of CDI less than 6 months after transplant) was found to be an independent risk factor for death among lung transplant recipients (HR 1.96, 95% confidence interval 1.14-3.36) [10]. Recent observational studies noted that approximately 3-4% of SOT recipients with CDI underwent colectomy, compared with less than 1% among the general hospitalized population [3,10,24].…”