2024
DOI: 10.1186/s12877-024-04960-z
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Cluster analysis dissecting cognitive deficits in older adults with major depressive disorder and the association with neurofilament light chain

Cynthia Yi-an Chen,
Chih-Chiang Chiu,
Cho-Yin Huang
et al.

Abstract: Background Cognitive impairment is a growing problem with increasing burden in global aging. Older adults with major depressive disorder (MDD) have higher risk of dementia. Neurofilament light chain (NfL) has been proven as a potential biomarker in neurodegenerative disease, including dementia. We aimed to investigate the association between cognitive deficits and NfL levels in older adults with MDD. Methods In this cross-sectional study, we enroll… Show more

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