At the microscopic level, the brain is fundamentally a matter of physics and chemistry, as all the components of the universe are. At the macroscopic scale, behavior, psychology and affects are the main dimensions of its life. To convert atoms and molecules into intelligence, some kind of information has to be fixed in the grey matter of the cerebral cortex. The way this "mental information" is materialized and processed is still an enigma, probably the most puzzling problem addressed to science nowadays. At this mesoscopic level of the brain functioning, the concepts to consider are likely the same as those considered in communication and information theory, mainly information, noise, coding and modulation. This paper proposes some ideas that could help understand some features of the brain in an information-processing perspective.