“…In particular, such renewed interest in manufacturing has also galvanized national policy-makers, which have put in place manufacturing-friendly initiatives and instruments in order to recreate a dense industrial base and related competencies, as well as to technologically upgrade the industrial base as a necessary condition for the long-term prosperity of their countries (De Backer, Menon, Desnoyers-James & Moussiegt, 2016 ). However, as industries are not evenly spread within countries (Boschma, 2015 ), national-level policies tend to have different impacts across regions, depending on their openness and connectivity to the world (Resmini, 2019 ), their degree of embeddedness in regional innovation systems (Parilli, 2019 ; Pietrobelli & Rebelloti, 2011 ), as well as on their comparative advantages and competitiveness (Neilson, Pritchard & Yeung, 2017 ). To address such regional heterogeneity, regional policy-makers are therefore tasked with designing specific initiatives that match the needs of local industries and firms in moving up their upgrading trajectory (Humphrey & Schmits, 2002 ).…”