Cn2 Use of Latent Variable and Survival Modeling to Estimate the Association of Patient-Reported Outcomes and Progression-Free Survival in Malignant Pleural Mesothelioma

Hackshaw,; Boye, Mark E.; West, TM; Prehn, AW

doi:10.1016/s1098-3015(10)72010-6

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sample size restrictions precluded such an analysis being conducted in our study. We must note that while such a bi-factor MIRT analysis would be cutting edge regarding its methodology, some work is yet to be done to demonstrate the clinical relevance and interpretability of MIRT questionnaires and adaptive tests, though multidimensional computer adaptive tests are beginning to emerge [ 72 ].…”

Section: Discussionmentioning

confidence: 99%

Electronic Quality of Life Assessment Using Computer-Adaptive Testing

Gibbons¹,

Bower²,

Lovell³

et al. 2016

J Med Internet Res

View full text Add to dashboard Cite

BackgroundQuality of life (QoL) questionnaires are desirable for clinical practice but can be time-consuming to administer and interpret, making their widespread adoption difficult.ObjectiveOur aim was to assess the performance of the World Health Organization Quality of Life (WHOQOL)-100 questionnaire as four item banks to facilitate adaptive testing using simulated computer adaptive tests (CATs) for physical, psychological, social, and environmental QoL.MethodsWe used data from the UK WHOQOL-100 questionnaire (N=320) to calibrate item banks using item response theory, which included psychometric assessments of differential item functioning, local dependency, unidimensionality, and reliability. We simulated CATs to assess the number of items administered before prespecified levels of reliability was met.ResultsThe item banks (40 items) all displayed good model fit (P>.01) and were unidimensional (fewer than 5% of t tests significant), reliable (Person Separation Index>.70), and free from differential item functioning (no significant analysis of variance interaction) or local dependency (residual correlations < +.20). When matched for reliability, the item banks were between 45% and 75% shorter than paper-based WHOQOL measures. Across the four domains, a high standard of reliability (alpha>.90) could be gained with a median of 9 items.ConclusionsUsing CAT, simulated assessments were as reliable as paper-based forms of the WHOQOL with a fraction of the number of items. These properties suggest that these item banks are suitable for computerized adaptive assessment. These item banks have the potential for international development using existing alternative language versions of the WHOQOL items.

show abstract

Section: Discussionmentioning

confidence: 99%