Co-exposure to titanium dioxide nanoparticles (NpTiO2) and lead at environmentally relevant concentrations in the Neotropical fish species Hoplias intermedius

Vicari, Taynah; Dagostim, Ana Carolina; Klingelfus, Tatiane; Galvan, Gabrieli Limberger; Monteiro, Patrícia Sampaio; Pereira, Letícia da Silva; Assis, Helena C. Silva de; Cestari, Marta Margarete

doi:10.1016/j.toxrep.2018.09.001

Cited by 31 publications

(9 citation statements)

References 86 publications

(122 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Noman et al [ 24 ] and Nyamukamba et al [ 25 ] described in detail the crystalline structure of anatase and rutile and the differences in their properties in their overview papers. The results of a morphology test of a sample of TiO 2 with the catalogue number 637254 carried out by Vicari et al [ 26 ] confirmed our presumption that anatase was spherical/oval particles. Despite the presence of impurity being rutile in the TiO 2 NPs sample, the specific surface area result obtained by us (81.6 m 2 /g) was very similar to the test results obtained by Vicari et al [ 26 ] (83.5 m 2 /g), who used an analogous sample of TiO 2 with the catalogue number 637254 in their tests.…”

Section: Discussionsupporting

confidence: 75%

“…The results of a morphology test of a sample of TiO 2 with the catalogue number 637254 carried out by Vicari et al [ 26 ] confirmed our presumption that anatase was spherical/oval particles. Despite the presence of impurity being rutile in the TiO 2 NPs sample, the specific surface area result obtained by us (81.6 m 2 /g) was very similar to the test results obtained by Vicari et al [ 26 ] (83.5 m 2 /g), who used an analogous sample of TiO 2 with the catalogue number 637254 in their tests. According to the producer’s data, the specific surface area of the TiO 2 NPs sample that we purchased should range from 45 m 2 /g to 55 m 2 /g [ 23 ], which is reported also, e.g., by Fiorenza et al [ 27 ] in their paper.…”

Section: Discussionsupporting

confidence: 75%

See 1 more Smart Citation

Preparation and Characterisation of Poly(methyl metacrylate)-Titanium Dioxide Nanocomposites for Denture Bases

et al. 2020

View full text Add to dashboard Cite

Introduction of titanium dioxide nanoparticles (TiO2 NPs) to poly(methyl methacrylate) (PMMA) aims to improve the mechanical, microbiological and tribological properties of dental prosthesis bases. The aim of the research was to assess the polymerisation time and the change in the colour of the new biomaterial. Samples with the 1 wt% and 2 wt% content of TiO2 additionally modified by ultrasounds were created. The effectiveness of ultrasounds was assessed by comparing the average size of conglomerates in a liquid acrylic resin monomer by means of a dynamic light scattering (DLS) analysis. The biomaterial structure was assessed by the energy-dispersive X-ray spectroscopy (EDS) analysis. The colour change was analysed by means of a colorimetric test and provided in the CIE (Commission internationale de l’éclairage) L*a*b* and RGB (Red Green Blue) colour palette. It was observed during the DLS test that the ultrasonic homogenisation process caused an increase in the suspension heterogeneity. The EDS analysis confirmed the presence of nanoparticles sized below 100 nm, which constitutes a ground for calling the new biomaterial a nanocomposite. The addition of TiO2 NPs as well as the ultrasounds result in the reduction of the average PMMA polymerisation time. The obtained data reveal that the addition of both 1 wt% and 2 wt% causes a considerable change in the PMMA colour: its whitening. To summarise, the reduced polymerisation time of the new biomaterial fully enables performance of standard procedures related to creation of dental prosthesis bases. Due to the considerable change in the colour, the clinical application is limited to performance of repairs or relining of the prosthesis, where the new material is located in an unaesthetic zone.

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Discussionsupporting

confidence: 75%

Preparation and Characterisation of Poly(methyl metacrylate)-Titanium Dioxide Nanocomposites for Denture Bases

et al. 2020

View full text Add to dashboard Cite

show abstract

“…On the opposite, TiO 2 NPs under UV light induced significant NAs at 10 mg L À1 . In addition, Vicari et al (2018) observed no significant increase in piscine MN in Hoplicus intermedius exposed to TiO 2 NPs (100% anatase) at 100 mg L À1 . Differences in results may most likely be due to the fish species utilized and different experimental conditions, such as illumination.…”

Section: Discussionmentioning

confidence: 77%

Titanium dioxide nanoparticles-induced cytogenotoxicity and alterations in haematological indices of Clarias gariepinus (Burchell, 1822)

et al. 2020

View full text Add to dashboard Cite

The application of titanium dioxide (TiO2) nanoparticles (NPs) in the manufacturing of consumer products has increased tremendously and with the potential to induce deleterious effects on aquatic biota. There have been reports on metal oxide NP toxicity in aquatic organisms, however, information on cytotoxicity and genotoxicity of TiO2 NPs on the African catfish, Clarias gariepinus, is scarce. In this study, we investigated the genotoxicity and haematotoxicity of TiO2 NPs in C. gariepinus using the micronucleus (MN) assay and haematological analysis, respectively. Juvenile C. gariepinus were exposed to 6.25, 12.5, 25.0, 50.0 and 100.0 mg L−1 concentrations of TiO2 NPs for 7 and 28 days. Benzene (0.05 mL L−1) and dechlorinated tap water were used as positive and negative controls, respectively. Data of the MN showed a significant ( p < 0.05) concentration-dependent increase in the frequency of MN at both exposure periods in comparison to negative control. Red blood cells, haematocrit, platelets and heterophils significantly reduced with an increased mean corpuscular haemoglobin concentration and lymphocytes at the 7-day exposure period, while in the 28-day exposure period, mean cell volume, mean corpuscular haemoglobin and lymphocytes had a significant increase in comparison with the negative control. This study indicates that TiO2 NPs induced cytogenetic and haematological alterations in C. gariepinus and is of relevance in biodiversity and aquatic health management.

show abstract

“…In the present study, no neurological disturbances of the cholinergic system were found in the brain after IP injection of TiO 2 NPs and BP-3, isolated or in mixture, for 3 and 7 days. In the same direction, several studies with freshwater fish reported no alterations in the AChE activity in the brain after waterborne exposure to TiO 2 NPs [46,[80][81][82][83]. On the contrary, waterborne exposure of the freshwater fish Carassius auratus to 200 µg L −1 of BP-3 promoted the increase in the activity of AChE [84].…”

Section: Neurotoxicitymentioning

confidence: 92%

Mild Effects of Sunscreen Agents on a Marine Flatfish: Oxidative Stress, Energetic Profiles, Neurotoxicity and Behaviour in Response to Titanium Dioxide Nanoparticles and Oxybenzone

Carvalhais

Pereira

Sabato

et al. 2021

IJMS

View full text Add to dashboard Cite

UV filters are potentially harmful to marine organisms. Given their worldwide dissemination and the scarcity of studies on marine fish, we evaluated the toxicity of an organic (oxybenzone) and an inorganic (titanium dioxide nanoparticles) UV filter, individually and in a binary mixture, in the turbot (Scophthalmus maximus). Fish were intraperitoneally injected and a multi-level assessment was carried out 3 and 7 days later. Oxybenzone and titanium dioxide nanoparticles induced mild effects on turbot, both isolated and in mixture. Neither oxidative stress (intestine, liver and kidney) nor neurotoxicity (brain) was found. However, liver metabolic function was altered after 7 days, suggesting the impairment of the aerobic metabolism. An increased motility rate in oxybenzone treatment was the only behavioural alteration (day 7). The intestine and liver were preferentially targeted, while kidney and brain were unaffected. Both infra- and supra-additive interactions were perceived, with a toxicodynamic nature, resulting either in favourable or unfavourable toxicological outcomes, which were markedly dependent on the organ, parameter and post-injection time. The combined exposure to the UV filters did not show a consistent increment in toxicity in comparison with the isolated exposures, which is an ecologically relevant finding providing key information towards the formulation of environmentally safe sunscreen products.

show abstract

Co-exposure to titanium dioxide nanoparticles (NpTiO2) and lead at environmentally relevant concentrations in the Neotropical fish species Hoplias intermedius

Abstract: Graphical abstract

Cited by 31 publications

References 86 publications

Preparation and Characterisation of Poly(methyl metacrylate)-Titanium Dioxide Nanocomposites for Denture Bases

Preparation and Characterisation of Poly(methyl metacrylate)-Titanium Dioxide Nanocomposites for Denture Bases

Titanium dioxide nanoparticles-induced cytogenotoxicity and alterations in haematological indices of Clarias gariepinus (Burchell, 1822)

Mild Effects of Sunscreen Agents on a Marine Flatfish: Oxidative Stress, Energetic Profiles, Neurotoxicity and Behaviour in Response to Titanium Dioxide Nanoparticles and Oxybenzone

Contact Info

Product

Resources

About