CO2 Laser-assisted Sclerectomy Surgery Part I

Ton, Yokrat; Geffen, Noa; Kidron, Dvora; Degani, Joshua; Assia, Ehud I.

doi:10.1097/ijg.0b013e31820e2ccd

Cited by 17 publications

(11 citation statements)

References 17 publications

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“…[10,11] CO 2 laser-assisted sclerectomy surgery (CLASS) is an enhanced adaptation of manual deep sclerectomy by using a CO 2 laser to ablate the scleral tissue leaving a thin membrane just enough for aqueous seepage, but without entering the anterior chamber since the laser energy is absorbed once there is seepage of aqueous.…”

Section: Introductionmentioning

confidence: 99%

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

et al. 2016

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To evaluate the efficacy and safety of CO2 laser-assisted sclerectomy surgery (CLASS) in Chinese patients with advanced glaucoma.Patients with advanced glaucoma who were candidates for glaucoma filtration surgery were included. The intraocular pressure (IOP) and number of antiglaucoma medications were documented before surgery and at all postoperative clinic visits. All intra- and postoperative complications were documented. The primary outcome measures were the changes in IOP and medication use before and after the procedure as well as complications from the procedure. The secondary outcome measure included the CLASS success rate.Twenty patients (23 eyes) underwent CLASS between November 2014 and September 2015. Nineteen eyes had primary open-angle glaucoma, 2 eyes had primary angle-closure glaucoma, and 2 eyes had uveitic glaucoma. One patient was lost to follow-up. The mean age of subjects was 68.1 ± 11.9 years. IOP was significantly reduced at 1 day and 1 week after CLASS. At 6 months, the IOP and number of medications were significantly reduced by 19.0% and 38.2%, respectively (both P < 0.0001). One patient had intraoperative trabeculo-Descemet membrane perforation. Two patients required laser goniopuncture and 2 required needling between 3 and 6 months postoperatively. The overall success rate was 81.8% at 6 months.CLASS achieved a modest IOP reduction in the early postoperative period and was overall a safe procedure for advanced glaucoma.

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Section: Introductionmentioning

confidence: 99%

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

et al. 2016

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“…CO 2 laser-assisted sclerectomy surgery (CLASS) is a recent modification of NPDS and has been implemented to overcome the technical difficulty of the manual technique (Assia et al 2007;Ton et al 2012). CO 2 laser energy has been found useful in sclerectomy as it provides accurate ablation of dry tissues and is absorbed by fluid, which means that the aqueous humour percolating through the intact TDM intrinsically prevents excessive ablation.…”

Section: Introductionmentioning

confidence: 99%

CO₂ laser‐assisted sclerectomy surgery compared with trabeculectomy in primary open‐angle glaucoma and exfoliative glaucoma. A 1‐year follow‐up

Jankowska-Szmul

Dobrowolski

Wylęgała

2018

Acta Ophthalmologica

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“…Ez a technológiai fejlesztés eredmé-nyezte azt, hogy a célszövet hatékony elpárologtatása mellett a környező szövetek termikus károsodása csak 200-250 µm kiterjedésű. Az ilyen módon effektív és minimális mellékhatással rendelkező technikával reprodukálhatóan hatékonnyá vált a CLASS-műtét, és a tanulási periódus is lerövidült [8,10,16,17].…”

Section: Következtetésekunclassified

CO₂-lézerrel végzett mélysclerectomiával szerzett tapasztalatok

Sohajda¹,

Káldi²,

Facskó

2017

Orvosi Hetilap

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Bevezetés: A CO 2 -lézeres mélysclerectomia (CLASS) a nyitott zugú glaucomás betegek sebészi kezelésében alkalmazható. Célkitűzés: A CLASS-műtéttel szerzett tapasztalataink ismertetése. Módszer: 21 CLASS-műtétet végeztünk OT-134-IOPtiMate (IOPtima Ltd, Ramat-Gan, Izrael) készülékkel. A betegeket a posztoperatív első napon, majd 1, 3, 6, 9 és 12 hónap múlva kontrolláltuk. Retrospektíven értékeltük a szemnyomás, antiglaucomás terápia és a visus alakulását, az intra-és posztoperatív szövődményeket. Eredmények: Az átlagéletkor 65,6 év volt. A teljes siker (szemcsepp nélkül elért célszemnyomás) a hatodik hónapra (18 beteg) 61,1%, míg a 12. hónapnál (10 beteg) 50% volt. A minősített siker (szemcseppel elért célszemnyomás) 72,2% és 70%, a preoperatív átlagos 29,2 ± 9,4 Hgmm-es szemnyomás rendre 17,7 ± 4,9 Hgmm és 17,3 ± 4,3 Hgmm volt. Jelentősen csökkent az antiglaucomás cseppek átlagos száma: 2,90 ± 0,83-ról 2,05 ± 1,46 értékre. Egy makroperforáción túl a műtét eredményességét befolyásoló egyéb lényeges szövődmény nem volt. Következtetések: CLASS-műtéttel tapasztalataink szerint hatékonyan csökkent-hető a szemnyomás nyitott zugú glaucomában. Orv Hetil. 2017; 158(18): 701-705. Kulcsszavak: CLASS, nyitott zugú glaucoma Experiences with CO 2 laser-assisted sclerectomy surgeryIntroduction: CO 2 laser-assisted sclerectomy surgery (CLASS) can be used for the surgical treatment of open-angle glaucoma. Aim: To introduce our results with CLASS. Method: We performed 21 CLASS operations using OT-134-IOPtiMate (IOPtima Ltd, Ramat-Gan, Israel). Patients were examined on the 1st day, and in the 1st, 3rd, 6th, 9th and 12th months postoperatively. We evaluated intraocular pressure (IOP), antiglaucomatous medication-use, visual acuity, complications. Results: Mean age was 65.6 yrs. Complete success (no hypotensive medication required to target IOP) was achieved in 61.1% (18 patients) at 6 months, whereas in 50% (10 patients) at 12 months. Qualified success (hypotensive medication required to target IOP) was achieved in 72.2% and in 70%, preoperative mean IOP was 29.2 ± 9.4 Hgmm, which falled to 17.7 ± 4.9 Hgmm and 17.3 ± 4.3 Hgmm, respectively. Antiglaucomatous medication use falled significantly from 2.90 ± 0.83 to 2.05 ± 1.46. Apart from 1 macroperforation, no serious complication occurred. Conclusions: With CLASS it is possible to effectively lower intraocular pressure in open-angle glaucoma.

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CO2 Laser-assisted Sclerectomy Surgery Part I

Abstract: The results in these experimental studies indicated that CO2 laser-assisted sclerectomy surgery using the OT-134 system is a safe and efficacious procedure for achieving effective fluid percolation.

Cited by 17 publications

References 17 publications

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

CO₂ laser‐assisted sclerectomy surgery compared with trabeculectomy in primary open‐angle glaucoma and exfoliative glaucoma. A 1‐year follow‐up

CO₂-lézerrel végzett mélysclerectomiával szerzett tapasztalatok

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CO2 Laser-assisted Sclerectomy Surgery Part I

Abstract: The results in these experimental studies indicated that CO2 laser-assisted sclerectomy surgery using the OT-134 system is a safe and efficacious procedure for achieving effective fluid percolation.

Cited by 17 publications

References 17 publications

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

Preliminary results of CO2 laser-assisted sclerectomy surgery (CLASS) in the treatment of advanced glaucoma in a Chinese population

CO2 laser‐assisted sclerectomy surgery compared with trabeculectomy in primary open‐angle glaucoma and exfoliative glaucoma. A 1‐year follow‐up

CO2-lézerrel végzett mélysclerectomiával szerzett tapasztalatok

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CO₂ laser‐assisted sclerectomy surgery compared with trabeculectomy in primary open‐angle glaucoma and exfoliative glaucoma. A 1‐year follow‐up

CO₂-lézerrel végzett mélysclerectomiával szerzett tapasztalatok