In China, south of the Yangtze River, there are a large number of carbon sources, while the Sichuan Basin is the largest sedimentary basin; it makes sense to select the targets for CO 2 geological storage (CGUS) early demonstration. For CO 2 enhanced oil and gas, coal bed methane recovery (CO 2 -EOR, EGR, and ECBM), or storage in these depleted fields, the existing oil, gas fields, or coal seams could be the target areas in the mesoscale. This paper proposed a methodology of GIS superimposed multisource information assessment of geological suitability for CO 2 enhanced water recovery (CO 2 -EWR) or only storage in deep saline aquifers. The potential per unit area of deep saline aquifers CO 2 storage in Central Sichuan is generally greater than 50 × 10 4 t/km 2 at P50 probability level, with Xujiahe group being the main reservoir. CO 2 storage potential of depleted gas fields is 53.73 × 10 8 t, while it is 33.85 × 10 8 t by using CO 2 -EGR technology. This paper recommended that early implementation of CGUS could be carried out in the deep saline aquifers and depleted gas fields in the Sichuan Basin, especially that of the latter because of excellent traps, rich geological data, and well-run infrastructures.