Cobalt, Linac, or Other: What Is the Best Solution for Radiation Therapy in Developing Countries?

Page, B.R.; Hudson, Alana; Brown, Derek; Shulman, Adam; Abdel‐Wahab, May; Fisher, Brandon J.; Patel, Shilpen

doi:10.1016/j.ijrobp.2013.12.022

Cited by 63 publications

(42 citation statements)

References 15 publications

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“…To-date, wide-ranging investigations have been made of the radiation dose detection capability of various types of passive dosimeters DeWerd et al, 2014;Halperin et al, 2014;Jafari et al, 2014;Marcazzó et al, 2013;Page et al, 2014;Pugliesi et al, 2014;Sahare et al, 2014;Salah et al, 2011;Twardak et al, 2014). The type of base material and constituent concentrations are the dominant factors influencing dosimeter performance.…”

Section: Introductionmentioning

confidence: 99%

Enhancing the radiation dose detection sensitivity of optical fibres

Bradley

Mahdiraji

Ghomeishi

et al. 2015

Applied Radiation and Isotopes

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Section: Introductionmentioning

confidence: 99%

Enhancing the radiation dose detection sensitivity of optical fibres

Bradley

Mahdiraji

Ghomeishi

et al. 2015

Applied Radiation and Isotopes

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“…RT and radiosurgery machines using radioactive sources are being replaced with linear accelerators (linacs). 2 Low activity sources can be used for brachytherapy. Furthermore, stereotactic RT combined with modern targeted therapies might soon make brachytherapy obsolete.…”

Section: Opening Statementmentioning

confidence: 99%

Medical use of all high activity sources should be eliminated for security concerns

Capala¹,

Goetsch²,

Orton³

2015

Medical Physics

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“…Unfortunately, these centers are operating in rural areas with economic disadvantage and hence cannot afford modern treatment planning or custom block fabrication. In a recent review in the red journal, Page et al 1 has cited the benefit of using multileaf collimator (MLC) to make Co-60 treatments on a par with high energy treatment machines. The benefit of using MLC for cobalt-60 was also referred by several investigators 2-8 .…”

Section: Introductionmentioning

confidence: 99%

DVH Analysis of Cobalt-60 treatment plans incorporating a recently developed MLC

Krishna

Akula²,

Kumar

et al. 2016

Int J Cancer Ther Oncol

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Purpose:The aim of this investigation was to measure the gain in DVH indices when the recently developed MLC was used for Cobalt-60 treatments. Methods: A prototype multileaf collimator (MLC) that was retrofitted to telecobalt-60 therapy machine was reported and is currently proposed for clinical trials in our institution. Ten patients' plans that were previously planned through an ECLIPSE ® treatment planning system and were treated with open beams from Cobalt-60 machine were imported into Radiation Oncology Planning System [ROPS] and the dose calculations and dose volume histogram (DVH) analysis were performed. The plans were re-planned using the Cobalt-MLC, a feature available in the ROPS planning system. The DVH analysis consisted of conformity index (CI), homogeneity index (HI) and conformation number (CN). The results of this study are presented in this paper. The analysis specifically aimed at measuring the gain in these indices when the MLC was compared with open beams. Results: DVH Comparison of ten sites using open and Cobalt MLC fields showed that the use of MLC results in reduced normal tissue dose, while maintaining the GTV dose. Lower value of CI for normal structures was observed demonstrating the sparing of critical organs when MLC was used. The index HI was studied to show the significance of hot spots outside the PTV. Hot spots were observed even with MLC beams for some cases due to less number of fields. Conclusion: It has been demonstrated through DVH analysis that the use of the recently developed MLC for Cobalt Teletherapy machine results in benefit for the treatment of patients.

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Cobalt, Linac, or Other: What Is the Best Solution for Radiation Therapy in Developing Countries?

Cited by 63 publications

References 15 publications

Enhancing the radiation dose detection sensitivity of optical fibres

Enhancing the radiation dose detection sensitivity of optical fibres

Medical use of all high activity sources should be eliminated for security concerns

DVH Analysis of Cobalt-60 treatment plans incorporating a recently developed MLC

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