Cocaine use is associated with worse outcomes in patients treated with thoracic endovascular repair for type B aortic dissection

Yammine, Halim; Krcelic, Daniel; Ballast, Jocelyn K.; Briggs, Charles S.; Stanley, Gregory A.; Nussbaum, Tzvi; Frederick, John R.; Arko, Frank R.

doi:10.1016/j.jvs.2018.10.061

Cited by 8 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This study reported an increased prevalence of cocaine-related AADs among young (41 ± 8.8 years), uncontrolled hypertensive (11/14, 79%), and smokers (14/14, 100%). Despite the fact that this is an inner-city location and single-center based study, which showed the highest prevalence of cocaine use in all the studies so far, six following studies confirmed these observations with a wide variation of cocaine use, ranging from 0.5% to 28%, and five of these studies reported that the majority of the cocaine users were male (71–88%) [ 207 , 208 , 209 , 210 , 211 , 212 ]. A previous IRAD report showed only 0.5% (5/921) patients with aortic dissection had a history of cocaine use in 2002 [ 207 ], while this proportion increased to 1.8% (63/3584) in 2014 [ 210 ].…”

Section: Introductionmentioning

confidence: 68%

“…However, the updated IRAD study found that cocaine-use patients had a higher risk of type B AAD (2.4%, 30/1252) than type A AAD (1.4%, 33/2332), which is consistent with a previous study [ 209 ]. Furthermore, Yammine et al [ 212 ] found that cocaine users were more likely to present with larger falser lumen diameters and higher risk of endoleaks among all the type B aortic dissection patients. This study also found more reinterventions in those cocaine-use patients, which confirmed the updated IRAD finding that a higher rehospitalization rate among the cocaine-use patients which possibly related to continuing cocaine use [ 210 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Risk Factors for Thoracic Aortic Dissection

Zhou

Cecchi

Prakash

et al. 2022

Genes

View full text Add to dashboard Cite

Thoracic aortic aneurysms involving the root and/or the ascending aorta enlarge over time until an acute tear in the intimal layer leads to a highly fatal condition, an acute aortic dissection (AAD). These Stanford type A AADs, in which the tear occurs above the sinotubular junction, leading to the formation of a false lumen in the aortic wall that may extend to the arch and thoracoabdominal aorta. Type B AADs originate in the descending thoracic aorta just distal to the left subclavian artery. Genetic variants and various environmental conditions that disrupt the aortic wall integrity have been identified that increase the risk for thoracic aortic aneurysms and dissections (TAD). In this review, we discuss the predominant TAD-associated risk factors, focusing primarily on the non-genetic factors, and discuss the underlying mechanisms leading to TAD.

show abstract

Section: Introductionmentioning

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Risk Factors for Thoracic Aortic Dissection

Zhou

Cecchi

Prakash

et al. 2022

Genes

View full text Add to dashboard Cite

show abstract

“…Studies were identified using the IBM Watson Analytics: Automating Visualization, Descriptive, and Predictive Statistics software, PubMed, and Google Scholar. As a result, we found five studies to which we compared our results [ 6 , 19 - 22 ] .…”

Section: Methodsmentioning

confidence: 99%

Cocaine-Related Aortic Dissection: what do we know?

Greve

Funke

Khairi

et al. 2020

Braz J Cardiovasc Surg

View full text Add to dashboard Cite

Introduction Cocaine use is known to be associated with an increased risk for vascular diseases. It is likely to trigger or increase the risk for an aortic dissection. We conducted an analysis of 45 cases of cocaine-related aortic dissection to further characterize the clinical features and outcomes of this patient cohort. Methods Our study cohort of 45 patients consisted of 11 cases from our institutional database and 34 published case reports. Results The observed cases of acute aortic dissection related to cocaine use showed a high proportion of young (41.3±8.67 years) and male (88.9%) patients. Most of the cases (75%) were classified as Stanford type A. Also, in 75% of the cases, cocaine use was prevalent for more than one year. Median time from last cocaine use to onset of symptoms was one hour. In-hospital mortality was 21.4%, while additional 11.9% of the cases died before arriving at the hospital. Conclusion Acute aortic dissection related to cocaine use occurs in predominantly young male patients and has a dismal outcome when compared to all comer series.

show abstract

“…В литературе регулярно встречаются сообщения о случаях расслоения аорты, ассоциированных с употреблением кокаина. Было опубликовано также несколько исследований по случаям острого расслоения аорты после употребления кокаина из регистров разных лет [36][37][38][39][40][41].…”

Section: васкулопатииunclassified

“…Еще в одном недавнем исследовании с большим количеством пациентов были проанализированы характеристики пациентов, подвергшихся торакальной эндоваскулярной репарации аорты по поводу расслоения типа В. В этой группе пациентов лица, употреблявшие кокаин (7,5%), также были курящими мужчинами негроидной расы с тенденцией к более обширному расслоению, эндопротеканию и с большей частотой повторных интервенций [40].…”

Section: васкулопатииunclassified

Cocaine as a Risk Factor for Heart and Vascular Disease. Part 1

Зыбалова¹,

Dostanko²,

Ягур³

et al. 2022

Кардиология В Беларуси

View full text Add to dashboard Cite

В обзоре приведены основные свойства, формы, метаболизм, фармакокинетика кокаина, возможные результаты его взаимодействия с другими веществами и лекарственными средствами, различные аспекты влияния кокаина на сердечно-сосудистую систему. Подробно рассмотрены механизмы действия кокаина, лежащие в основе развития основных широко распространенных патологических процессов в сердце и сосудах. Проанализированы данные большого числа опубликованных исследований, посвященных влиянию кокаина на развитие различных нарушений проводимости и ритма сердца, артериальной гипертензии, эндотелиальной дисфункции, расслоение крупных артерий и аорты. Также обсуждены особенности действия кокаина в разных группах пациентов и в зависимости от длительности его употребления. Приведены рекомендации по диагностике и выбору терапии при ряде патологических состояний, связанных с употреблением кокаина. Особое внимание уделено спорным вопросам лечения и влияния кокаина на сердце и сосуды, диагностическим возможностям различных методов исследования. The review presents the main properties, forms, metabolism, pharmacokinetics of cocaine, possible results of its interaction with other substances and medicines, various aspects of cocaine effect on the cardiovascular system. The mechanisms of cocaine action underlying the development of the main widespread pathological processes in the heart and blood vessels, are considered in detail. The data of a large number of published studies on the cocaine influence on the development of various disorders of conduction and heart rhythm, arterial hypertension, endothelial dysfunction, and dissection of large arteries and aorta are analyzed. The particulars of action with the duration of cocaine use as well as in different groups of patients are discussed. Recommendations are given for the diagnostics and choice of therapy for a number of pathological conditions associated with cocaine use. Particular attention is paid to controversial issues of treatment and effect of cocaine on the heart and blood vessels, the diagnostic capabilities of various diagnostic methods.

show abstract

Cocaine use is associated with worse outcomes in patients treated with thoracic endovascular repair for type B aortic dissection

Cited by 8 publications

References 31 publications

Risk Factors for Thoracic Aortic Dissection

Risk Factors for Thoracic Aortic Dissection

Cocaine-Related Aortic Dissection: what do we know?

Cocaine as a Risk Factor for Heart and Vascular Disease. Part 1

Contact Info

Product

Resources

About