Coffee pulp supplement affects antioxidant status and favors anti‐aging of skin in healthy subjects

Tseng, Ya-Ping; Liu, Cheng; Chan, Leong‐Perng; Liang, Chia-Hua

doi:10.1111/jocd.14341

Cited by 11 publications

(8 citation statements)

References 39 publications

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“…Polyphenols were tested in nine researches ( n = 495) as single-preparation products. The active ingredients involved in the studies included procyanidin ( 69 – 72 ) (4 studies), flavanol ( 73 , 74 ) (2 studies), and coffee polyphenols ( 75 , 76 ) (2 studies), and green tea polyphenols ( 77 ) (1 studies). The dosages of polyphenols were mentioned in eight researches within a range of 15 to 1,400 mg every day over 6 to 12 weeks.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Sun

Wu²,

Qian³

et al. 2022

Front. Nutr.

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BackgroundThe dietary supplement industry offers many oral cosmetics that purportedly assist in skin moisturization often with unclear evidence supporting efficacy and safety. To update the accessible proofs pertaining to the safety and effectiveness of oral dietary supplements to facilitate skin moisturizing via an all-around review and meta-analysis.MethodsThree on-line databases [Pubmed, Embase, and Cochrane Library (CENTRAL)] were retrieved from January 2000 to November 2021. An overall 66 randomized controlled trials (RCTs) of skin care were recognized. Meta-analysis was performed for dietary supplements with four or more available research.ResultsOral collagen or ceramide resulted in a statistically significant increase in skin hydration and a decrease in transepidermal water loss (TEWL) compared to placebo. No benefits regarding the improvement of skin conditions in terms of water content and TEWL were observed for lactic acid bacteria or Lactobacillus fermented foods. A statistically significant and positive effect on skin hydration was observed for both hyaluronan and procyanidin, with an unknown effect on TEWL due to insufficient RCTs. There was a non-significant improvement in the water content of stratum corneum for astaxanthin based on subgroup analyses. Among the dietary supplements trialed in ≤ 3 RCTs, the judgment regarding their effects on skin moisturizing was prevented by inconsistent conclusions as well as insufficient research. All food supplements were safe throughout the research (normally ≤ 24 weeks).ConclusionOral dietary supplements, including collagen, ceramides, hyaluronan, and procyanidin, were proven to be effective for skin moisturization. At present, for skin moisturization, the proofs supporting the recommendation of other dietary supplements, such as lactic acid bacteria and astaxanthin, are insufficient.Systematic Review Registrationhttp://www.crd.york.ac.uk/PROSPERO/ identifier CRD42021290818

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Section: Resultsmentioning

confidence: 99%

Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Sun

Wu²,

Qian³

et al. 2022

Front. Nutr.

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“…Thus, proving the delay in ageing effects of coffee extract in nutraceutical segment. 25 Over the years, the botanicals extracted from amla, green tea, and coffee are implemented in skin care regimen protecting the skin from harmful effects on chronological and accelerated ageing. However, the combination of these potent polyphenol rich plant materials in CollaBZen TM , until now, were not investigated for its potential to enhance collagen production invitro and combat signs of ageing in human volunteers.…”

Section: Discussionmentioning

confidence: 99%

Anti-ageing effects of CollabZen™ in healthy human volunteers: a randomized, double blind, placebo-controlled study

Gadani,

Badak,

Upadhyay

2024

Int J Clin Trials

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Background: There are several concerns related to combating signs of ageing. Considering the long-term safety concerns of cosmetic formulations, a safe and effective approach using nutritional supplements and naturals should be of great help. CollabZenTM is one such a blend of three plant materials known as Phyllanthus emblica, Camellia sinensis, and Coffea arabica, earlier tested for collagen building in human cells in-vitro. The current study aims to explore its potential as a nutraceutical product for skin ageing. Methods: The study enrolled 64 volunteers both genders (mean age=45.75) with crow's feet wrinkles. One group (n=32) received a placebo capsule (Product A) and other group received CollabZenTM capsules (Product B). Dermatological parameters were assessed at 0th day, 4th and 8th week, and self-assessment questionnaires for efficacy and tolerance were collected on 4th and 8th week. The trial is registered at https://ctri.nic.in/, CTRI/2022/10/046168. Results: The results showed that product B (CollabZenTM) was significantly effective than the placebo in improving deep skin hydration on the face (p=0.009), increasing facial skin elasticity (p=0.001), and enhancing firmness (p=0.001) after 8 weeks. Participants in Group B reported higher levels of satisfaction regarding their perceived skin health compared to group A based on self-assessment at the 8th weeks (p<0.01). Moreover, only one volunteer in each group experienced mild intolerance at the end of 8th week, demonstrating the safety of these nutraceutical ingredients and excipients. Conclusions: CollabZenTM, with its known antioxidant and collagen-boosting properties and current findings can be considered a valuable nutraceutical product for the anti-ageing sector of the cosmetic industry.

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“…A 2021 study evaluated the antioxidant status and antiaging properties of coffee pulp supplements at a concentration of 14% as a drink and a 2% concentration of serum application groups and the results were suggestive of reducing free radical activities, thereby delaying the skin aging process and enhancing skin health. [ 17 ]…”

Section: Discussionmentioning

confidence: 99%

Coffee pulp: From a by-product of coffee production to a potential anticariogenic mouth rinse! An in vivo study

Bollamma,

Nanjamma,

Ponnappa

2023

Journal of Conservative Dentistry and Endodontics

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Background and Objectives: Dental caries is a prevalent disease despite various efforts made toward its prevention. The drawbacks of the available preventive agents have led to the quest for a potentially more effective agent with fewer adverse effects. Coffee, a local produce of Coorg, is one such herbal alternative. This study aims to assess the potential antimicrobial activity of Robusta coffee pulp extracts on Streptococcus mutans . Methodology: A total of 39 participants were divided into three groups with 13 participants each, after obtaining ethical clearance and informed consent: Group A (negative control), sterile water; Group B (positive control), 0.2% chlorhexidine mouth rinse; and Group C, 2.5% coffee pulp extract rinse (prepared according to minimum inhibitory concentration). The saliva samples were collected from the patients in a sterile Eppendorf tube at prerinse for baseline, at 1-h postrinse, and at the end of 2 weeks. The S. mutans colony count was done using image-based software analysis. The acquired data were statistically analyzed with one-way ANOVA and repeated measures ANOVA followed by post hoc Tukey’s test. Results: Coffee pulp mouth rinse ( P = 0.035) and positive control ( P = 0.036) groups showed a statistically significant reduction in the microbial count at 2 weeks postrinse (compared to the negative control group). Conclusion and Clinical Relevance: The coffee pulp extract-based mouth rinse is a potential anticariogenic agent that offers few advantages over chlorhexidine as no instances of staining, altered taste, or any allergic reactions were reported by the subjects.

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Coffee pulp supplement affects antioxidant status and favors anti‐aging of skin in healthy subjects

Cited by 11 publications

References 39 publications

Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Anti-ageing effects of CollabZen™ in healthy human volunteers: a randomized, double blind, placebo-controlled study

Coffee pulp: From a by-product of coffee production to a potential anticariogenic mouth rinse! An in vivo study

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