The present research comprised of two phases. The major aim of the study was translated and adapted CBT workbook of Anger Management in patients with substance used disorder as well as to find the efficacy of Urdu translated version. In the first phase of study Anger management workbook for substance abuse disorders was translated into Urdu following the forward-backward standardized translation procedures (MAPI, 2011). During second phase the efficacy of Urdu translated version was explored. It is hypothesized that Urdu version of CBT Anger Management Workbook was helpful to reduce anger in patient with substance related disorder. Gender difference was also speculated regarding study variables. Repeated measures design was used for pre- testing and post - testing. With the help of convenient sampling, 30 patients including 15 men and 15 women were drawn from private addiction clinics of Lahore. Assessment measures including Clinical Anger Scale and Drug Abuse Screen Test was used for data collection. Urdu translated version of Clinical Anger Scale was used. Descriptive analysis was carried out for all study variables. Independent sample t- test was used to examine the gender difference and results showed that men achieved all targeted treatment goals as compared to women. Paired sample t– test was used for Pre- test Clinical Anger Scale and Post- test Clinical Anger Scale and There is significance difference in pre-testing and post testing as results showed, on all items of Clinical Anger Scale that described anger management effectively work on substance used clients.