Cognitive Performance and Functional Competence as Predictors of Community Independence in Schizophrenia

Heinrichs, R. Walter; Ammari, Narmeen; Miles, A. A.; Vaz, Stephanie McDermid

doi:10.1093/schbul/sbn095

Cited by 44 publications

(30 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We agree to the consensus that schizophrenia is marked by cognitive impairments that do not appear to be secondary to symptoms and point to localized brain dysfunction. The addition of functional competence to standard cognitive test data [25] yields a significant increase in validity only for concurrent and not for longitudinal prediction of community independence. The specific real-world validity of functional competence is modest and this information is largely redundant with standard cognitive performance.…”

Section: Discussionmentioning

confidence: 99%

Neuropsychological functioning in inpatients with major depression or schizophrenia

Schaub¹,

Neubauer

Mueser

et al. 2013

BMC Psychiatry

View full text Add to dashboard Cite

BackgroundStudies that compare neuropsychological functioning in inpatients with mood disorder or schizophrenia come to heterogeneous results. This study aims at investigating the question whether there are different neuropsychological test profiles in stabilised post-acute inpatients with affective disorders or schizophrenia.MethodWe were interested in evaluating impairment in specific areas of cognitive functioning in patients with schizophrenia or depression. In clinical reality, patients with depression and schizophrenia are often treated together with little attention to their specific needs. 74 patients with major depression and 38 patients with schizophrenia were assessed in a comprehensive neuropsychological battery. All patients were in a post-acute stage of their illness, i.e. remission of acute symptoms.ResultsIn spite of a comparable mean score of psychopathological symptoms in the Brief Psychiatric Rating Scale-Expanded (BPRS-E) as well as in the Global Assessment Functioning Scale (GAF), patients with depressive disorder showed significantly better results in verbal and visual short-term memory, verbal fluency, visual-motor coordination, information processing in visual-verbal functioning and selective attention compared to patients with schizophrenia. No significant differences between both samples were found in practical reasoning, general verbal abstraction, spatial-figural functioning, speed of cognitive processing.ConclusionsThese results show that there are differences in scores in psychopathology (BPRS-E, GAF) in patients with affective disorders or schizophrenia and different neuropsychological test profiles in the post-acute stage of their illness.

show abstract

Section: Discussionmentioning

confidence: 99%

Neuropsychological functioning in inpatients with major depression or schizophrenia

Schaub¹,

Neubauer

Mueser

et al. 2013

BMC Psychiatry

View full text Add to dashboard Cite

show abstract

“…One study 47 assessed the relation between cognition, functional capacity, and real-world functional outcomes. Among 127 patients with schizophrenia or schizoaffective disorder, cognition predicted performance on a composite, real-world functional outcome measure at residence, schooling, and work during a 10-month follow-up period.…”

Section: Relations Between Cognition and Other Variables In Predictinmentioning

confidence: 99%

Cognition, Function, and Disability in Patients with Schizophrenia: A Review of Longitudinal Studies

2014

View full text Add to dashboard Cite

This paper aims to review longitudinal studies assessing the impact of cognition on function in patients with schizophrenia. PubMed and Scholars Portal were searched using search terms related to schizophrenia, cognition, function, and longitudinal studies. Some functional abilities have been studied more than others. Some studies suggest that the impact of cognition on function depends on the severity of baseline cognitive deficits. Other studies suggest that the impact of cognition on function depend on what phase of the illness the patient is in or what stage in that particular function the patient is involved in. Finally, few studies assessed interactions between cognition and other aspects of schizophrenia in predicting function, such as functional capacity, insight, motivation, and negative symptoms. More longitudinal and comprehensive studies are needed. A focus on community living is of high public significance as patients with schizophrenia continue to grow old. Future studies should also focus on the longitudinal interactions between cognition and other dimensions of schizophrenia as well as on the biological factors that underlie these interactions. W W W Cognition, fonction et incapacité chez des patients souffrant de schizophrénie : une revue des études longitudinalesCet article vise à examiner les études longitudinales évaluant l'effet de la cognition sur la fonction des patients souffrant de schizophrénie. Des recherches ont été effectuées dans PubMed et Scholars Portal à l'aide de mots clés liés à la schizophrénie, la cognition, la fonction, et les études longitudinales. Certaines capacités fonctionnelles ont été étudiées plus que d'autres. Des études suggèrent que l'effet de la cognition sur la fonction dépend de la gravité des déficits cognitifs au départ. D'autres études font valoir que l'effet de la cognition sur la fonction dépend de la phase de la maladie ou du stade de cette fonction où se situe le patient. Enfin, peu d'études ont évalué les interactions entre cognition et autres aspects de la schizophrénie pour prédire la fonction, comme la capacité fonctionnelle, l'intuition, la motivation, et les symptômes négatifs. Il faut plus d'études longitudinales et exhaustives. Mettre l'accent sur la vie dans la communauté est d'une grande importance publique car les patients souffrant de schizophrénie continuent de vieillir. Les futures études devraient aussi se pencher sur les interactions longitudinales entre la cognition et d'autres dimensions de la schizophrénie, ainsi que sur les facteurs biologiques qui sous-tendent ces interactions.S chizophrenia affects more than 24 million adults, worldwide, and about a quarter of a million in Canada.

show abstract

“…Leifker et al (Liefker et al, 2009) suggested that performance-based measures of everyday functioning are more directly related to everyday functioning than NP test performance, although other studies have found slightly different results (Heinrichs et al, 2010). Severity of symptoms negatively impacts on everyday functioning in the absence of major correlations with either NP test performance or functional capacity (Bowie et al, 2008, 2010).…”

Section: Introductionmentioning

confidence: 99%

The course and correlates of everyday functioning in schizophrenia

Reichenberg

Feo

Prestía

et al. 2014

Schizophrenia Research: Cognition

View full text Add to dashboard Cite

Previously institutionalized older patients with schizophrenia show changes in cognitive and functional capacity over time. This study examined changes in real-world functioning in a sample of people with schizophrenia who varied in their history of long-term institutionalization and related changes in real world functioning to changes in cognition and functional capacity over the follow-up period. Older patients with schizophrenia (n=111) were examined with assessments of cognitive functioning, functional capacity, clinical symptoms, and everyday functioning. They were then followed up to 45 months and examined up to two times. Mixed-model regression was used to examine changes in real-world functioning in social, everyday living, and vocational domains over the follow-up period and identify potential predictors of change. Everyday functioning worsened over time in all three domains. Although length of longest hospitalization predicted worsening, this influence was eliminated when the course of functional capacity was used to predict the course of everyday functioning. For both vocational and everyday living domains, as well as the composite score on functional status, worsening in performance based measures of everyday functioning and social competence predicted worsening in real world functioning. Changes in negative symptoms further predicted worsening in the everyday living domain. Worsening in everyday functioning is found in people with schizophrenia and those with a history of greater chronicity and severity of illness seem more affected. These influences seem to be expressed through worsening in the ability to perform everyday functional skills. Potential causes of these changes and implications for reducing these impairments are discussed.

show abstract

Cognitive Performance and Functional Competence as Predictors of Community Independence in Schizophrenia

Cited by 44 publications

References 29 publications

Neuropsychological functioning in inpatients with major depression or schizophrenia

Neuropsychological functioning in inpatients with major depression or schizophrenia

Cognition, Function, and Disability in Patients with Schizophrenia: A Review of Longitudinal Studies

The course and correlates of everyday functioning in schizophrenia

Contact Info

Product

Resources

About