Cognitive rehabilitation in multiple sclerosis

Longley, Wendy A.

doi:10.31128/ajgp-08-21-6146

Cited by 6 publications

(2 citation statements)

References 32 publications

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“…The underlying mechanisms explaining these beneficial effects correlate with the enhancement of functional and structural neuroplasticity, dependent on the trained cognitive tasks [74]. In addition, cognitive rehabilitation may induce beneficial neurobiological changes in the hypothalamic-pituitaryadrenal axis, improving the regulation of serotonin precursors and neurogenesis via direct mechanisms and also as an indirect effect that occurs with the decrease in the stress and depression level [75]. Once a personalized neuropsychological assessment is completed, the therapy can be tailored according to the individual needs of each MS patient.…”

Section: The Impact Of Medication and Cognitive Rehabilitation On Cog...mentioning

confidence: 99%

“…A broad range of cognitive rehabilitation methods are currently available and can be classified into two categories: compensatory approaches and restorative interventions. Both therapists and patients have preferred practical compensatory approaches, as they show usefulness in the activities of daily living [75]. The use of reminder devices and workplace adjustments was demonstrated to be particularly effective in MS patients with mild to moderate memory and attention problems.…”

Section: The Impact Of Medication and Cognitive Rehabilitation On Cog...mentioning

confidence: 99%

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Risk Factors for Cognitive Impairment in Multiple Sclerosis Patients

Schreiner,

Mihoc,

Grigore

et al. 2024

Sclerosis

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Cognitive impairment is one of the most significant burdens among the many neurological complaints in multiple sclerosis patients. Cognitive deficits negatively impact these patients’ quality of life, leading to partial or total loss of several mental functions, such as learning, memory, perception, or problem-solving. While the precise mechanisms involved in the onset and evolution of cognitive decline remain unknown, several risk factors have been associated with intellectual disability. With increasing data on this topic in recent years, the main aim of this review is to summarize the most relevant risk factors correlated with cognitive impairment in multiple sclerosis patients. Firstly, the authors demonstrate the importance of mental disability based on epidemiological data from multiple sclerosis patient cohorts. Subsequently, the intensely debated major risk factors for cognitive decline are discussed, with brief insights into the pathophysiology and possible underlying mechanisms. Finally, the authors describe the impact of medication on cognitive impairment in multiple sclerosis patients, highlighting the main research directions for future studies.

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Section: The Impact Of Medication and Cognitive Rehabilitation On Cog...mentioning

confidence: 99%

Section: The Impact Of Medication and Cognitive Rehabilitation On Cog...mentioning

confidence: 99%

Risk Factors for Cognitive Impairment in Multiple Sclerosis Patients

Schreiner,

Mihoc,

Grigore

et al. 2024

Sclerosis

View full text Add to dashboard Cite

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Delivery of Neuropsychological Interventions for Adult and Older Adult Clinical Populations: An Australian Expert Working Group Clinical Guidance Paper

Wong,

Pike,

Stolwyk

et al. 2023

Neuropsychol Rev

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Delivery of neuropsychological interventions addressing the cognitive, psychological, and behavioural consequences of brain conditions is increasingly recognised as an important, if not essential, skill set for clinical neuropsychologists. It has the potential to add substantial value and impact to our role across clinical settings. However, there are numerous approaches to neuropsychological intervention, requiring different sets of skills, and with varying levels of supporting evidence across different diagnostic groups. This clinical guidance paper provides an overview of considerations and recommendations to help guide selection, delivery, and implementation of neuropsychological interventions for adults and older adults. We aimed to provide a useful source of information and guidance for clinicians, health service managers, policy-makers, educators, and researchers regarding the value and impact of such interventions. Considerations and recommendations were developed by an expert working group of neuropsychologists in Australia, based on relevant evidence and consensus opinion in consultation with members of a national clinical neuropsychology body. While the considerations and recommendations sit within the Australian context, many have international relevance. We include (i) principles important for neuropsychological intervention delivery (e.g. being based on biopsychosocial case formulation and person-centred goals); (ii) a description of clinical competencies important for effective intervention delivery; (iii) a summary of relevant evidence in three key cohorts: acquired brain injury, psychiatric disorders, and older adults, focusing on interventions with sound evidence for improving activity and participation outcomes; (iv) an overview of considerations for sustainable implementation of neuropsychological interventions as ‘core business’; and finally, (v) a call to action.

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