Cohort study of mesenteric panniculitis and its relationship to malignancy

Abstract

MP does not behave like a paraneoplastic phenomenon. The association with malignancy is most likely an epiphenomenon of the many CT images acquired for staging of cancer.

Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain

“…Lymphoma was the most common malignancy followed by prostate, melanoma, lung and renal cell cancer. 18,19 Furthermore; studies have shown association of SM with conditions like sclerosing cholangitis, Riedel thyroiditis, mixed connective tissue disease, ankylosing spondylitis, Sjogren's syndrome tuberculosis, acute pancreatitis and granulomatous diseases. 1,13,20 Only significant finding in our patient was partially incarcerated hernia.…”

The Complex Relationship between Mesenteric Panniculitis and Malignancy — A Holistic Approach is Still Needed to Understand the Diagnostic Uncertainties

“…Malignancy was identified in 45 patients (38%) (34 males). The most common malignancies were colorectal (14), lymphoma (13), and urogenital tract (7). Malignancies were diagnosed after the detection of mesenteric panniculitis in 13 patients.…”

Mesenteric panniculitis: diagnostic precision

“…The imaging findings of MP are not specific and reflect the existence of an inflammatory process of the mesenterium that occurs both on inflammation and tumorous pathologies. [2][3][4][5][6][7] Moreover, MP has also been reported in association with systemic vasculitis such as Henoch-Schönlein purpura. 9 The imaging findings to the diagnosis of MP is based on typical CT features that include a mass effect of neighbouring gastrointestinal structures, a mesenteric slightly heterogenous well-circumscribed fatty proliferation surrounded by a peripheral capsule and internal small soft tissue nodules surrounded by a hypoattenuating halo.…”

“…[1][2][3][4] Definitive treatment for MP is still controversial in the medical literature with both medical and surgical approaches referred. For medical treatment, prednisolone, azathioprine, tamoxifen, thalidomide, antibiotics, infliximab and cyclophosphamide have been studied as acceptable options.…”

“…1 MP is an idiopathic disease but it has been associated with cancers, intra-abdominal surgery, ischaemic heart disease or autoimmune disorders on scientific literature. [1][2][3][4] The clinical presentation of the patients is diverse, but more frequently they present with abdominal pain, weight loss, fever, nausea and vomiting. The diagnosis is histopathological.…”