Colchicine Therapy for Refractory Idiopathic Thrombocytopenic Purpura

Strother, S. Vance

doi:10.1001/archinte.1984.04400020110017

Cited by 41 publications

(3 citation statements)

References 15 publications

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“…As with non‐pregnant adults and paediatric ITP, platelet‐associated IgG is of no diagnostic value. Despite recent innovative methodologies, measurement of serum platelet autoantibodies are not clearly diagnostic of ITP in individual patients and do not predict the likelihood of neonatal thrombocytopenia (Burrows & Kelton, 1992; Letsky & Greaves, 1996; Sainio et al, 1998; Boehlen et al, 1999).…”

Section: Idiopathic (Autoimmune) Thrombocytopenia (Itp)mentioning

confidence: 99%

“…Attempts have been made to predict which neonates will have severe thrombocytopenia to inform management decisions. It is reported (evidence level III) that the fetal or neonatal platelet count cannot be reliably predicted from the maternal platelet count, maternal platelet antibody levels (by a variety of techniques) or a history of maternal splenectomy for ITP (Samuels et al, 1990; Burrows & Kelton, 1992; Letsky & Greaves, 1996; Sainio et al, 1998; Boehlen et al, 1999). Fetal blood sampling by cordocentesis has been explored (Scioscia et al, 1988) but this procedure carries a mortality of 1–2%, which is at least as high as the risk of ICH.…”

Section: Management Of Delivery and The Newborn Infantmentioning

confidence: 99%

See 1 more Smart Citation

Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy

Provan¹,

Newland²,

Norfolk³

et al. 2003

Br J Haematol

696

105

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Section: Idiopathic (Autoimmune) Thrombocytopenia (Itp)mentioning

confidence: 99%

Section: Management Of Delivery and The Newborn Infantmentioning

confidence: 99%

Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy

Provan¹,

Newland²,

Norfolk³

et al. 2003

Br J Haematol

696

105

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“…Gli alcaloidi della Vinca hanno un effetto simile, e perciò è stato suggerito che i due farmaci possano avere un effetto sinergico. Due casistiche su adulti degli anni '80 (Strother et al, 1984;Jim 1986) riportano dati contrastanti sull'efficacia della colchicina. Una terza casistica di sei pazienti adulti ha osservato una risposta completa in 4 e parziale in 2.…”

Section: Colchicina E Idrossiclorochinaunclassified

Sport and Children with Immune Thrombocytopenia: Never Give Up

Lassandro

Palmieri

Palladino

et al. 2019

Curr Sports Med Rep

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In blu la sigla o la definizione ricorrente nel testo, in grigio l'esplicitazione inglese della sigla, in nero la corrispondente spiegazione in italiano AIEOP Associazione Italiana di Ematologia ed Oncologia Pediatrica AIHA Auto-Immune Hemolytic Anemia, anemia emolitica autoimmune ALPS Autoimmune LymphoProliferative Syndrome, Sindrome Linfoproliferativa Autoimmune ANA Anti-nuclear antibody, anticorpi anti nucleo Anti-D Immunoglobuline anti-D ASH American Society of Hematology CFS chronic fatigue syndrome, sindrome da affaticamento cronico DAT direct antiglobulin test, test di Coombs diretto DTP difterite tetano pertosse e.v. endo-vena Fab Fragment Antigen Binding, frammento legante l'antigene FDA Food and Drug Administration, Agenzia per gli Alimenti e i Medicinali GdL Gruppo di Lavoro "Difetti della Coagulazione" HD DXM desametazone ad alte dosi Hp Helicobacter pylori ICIS Intercontinental Cooperative ITP Study Group ITP Immune ThrombocytoPenia , TrombocitoPenia Immune IVIG Immunoglobuline endo-vena IWG International Working Group LES lupus eritematoso sistemico MMF micofenolato mofetile MMR measles mumps rubella, morbillo, parotite, rosolia m-PDN metil-prednisolone mTOR mammalian target of rapamicin MYH9 Myosin heavy chain 9, NTDT Non-transfusion-dependent thalassaemia, talassemia non trasfusione dipendente OPSI overwhelming post splenectomy infection, infezioni gravi post-splenectomia OR Odds Ratio PCR Polymerase Chain Reaction, Reazione a Catena della Polimerasi QoL Quality of life, qualità di vita RC risposta completa RP risposta parziale TCR T-cell receptor, recettore delle cellule T TPO trombopoietina T-reg regulatory T cells, cellule T regolatorie la gestione sarà presa dal curante alla luce dei dati personali del paziente e degli strumenti diagnostici e terapeutici disponibili.

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Immunotherapy of Idiopathic Thrombocytopenic Purpura and Autoimmune Neutropenia

Wordell

1987

Pharmacotherapy

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Idiopathic thrombocytopenic purpura (ITP) is a disorder characterized by a low platelet count and purpura. Identification of an antiplatelet antibody suggests that this is an autoimmune disease. Corticosteroids and splenectomy have been the major therapies for many years. High-dose intravenous immune globulin (IV-IgG) has been very successful in the management of ITP and has recently received FDA approval for this condition. It was also successful when administered to a few patients with autoimmune neutropenia. The exact mechanism of action of IV-IgG in autoimmune disorders is poorly understood. Currently, high-dose IV-IgG has a definite place in the management of ITP. Its role in therapy includes emergency treatment, preoperative preparation, the postponement of splenectomy in young children, and treatment of ITP during pregnancy.

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Colchicine Therapy for Refractory Idiopathic Thrombocytopenic Purpura

Cited by 41 publications

References 15 publications

Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy

Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy

Sport and Children with Immune Thrombocytopenia: Never Give Up

Immunotherapy of Idiopathic Thrombocytopenic Purpura and Autoimmune Neutropenia

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