Coleta de células progenitoras periféricas por aférese automatizada em equino: relato de procedimento

Bernardo, J. O.; Escodro, Pierre Barnabé; Notomi, Marcia Kikuyo; Roveri, Eduardo Gasparotto; Nascimento, Ticiano Gomes do

doi:10.1590/1678-4162-9124

Cited by 2 publications

(2 citation statements)

References 9 publications

(7 reference statements)

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“…Santos (2017) describes that in domestic animals the most used source for isolation and culture of stem cells is adipose tissue, as does Oliveira (2019), who published a work collecting adipose tissue in horses, in the region parallel to the base of the tail, through a 4 to 5 cm skin incision reaching the adipose tissue between the skin and the muscles. However, Bernardo et al (2017) carried out a study in horses, describing a technique for obtaining stem cells from the bloodstream, called peripheral progenitor cells. Where he reported that it is an easy technique to perform, being possible in an outpatient environment, as it is only necessary to access the equine vein without the need for anesthesia or sedation and with a lower risk of contamination.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Biological Membrane and Stem Cells as Potential Repairs of Tenorraphy in Wistar Rats

Coutinho,

Rangel,

Santos

et al. 2024

JASR

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Tendon rupture and lacerations are orthopedic problems of great importance in veterinary medicine. Many times, animals are discarded or removed from athletic life due to ruptured tendons. Therefore, new therapeutic possibilities have been used to improve and accelerate tendon healing. The objective of the work was to evaluate the use of a biological membrane derived from bovine tunica albuginea and stem cells in tenorrhaphies in veterinary medicine. Thirtyone adult Wistar rats were used, subdivided into 4 experimental groups, the control group (CG) with 4 animals, the tenotomy group (GT), the biological membrane group (GMB) and the stem cell group (GCT), each with 9 animals. The albugineous tunics were collected and underwent cleaning, conservation and quality analysis, making them ready for use. Three young Wistar rats were used to extract subcutaneous adipose tissue for stem cell cultivation. After the surgeries, the animals were euthanized in 3 moments; 7, 14 and 21 days postoperatively, where they were evaluated macroscopically and microscopically. The GT and GMB demonstrated low quality of healing and inflammation at almost all evaluated moments. The GCT presented a much better result, in relation to all the parameters evaluated between the groups, low tendon inflammation, no limb edema, much higher quantity and quality of collagen and demonstrating rapid healing and high tissue quality. We conclude that stem cell therapy in cases of tendon ruptures is very promising.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Biological Membrane and Stem Cells as Potential Repairs of Tenorraphy in Wistar Rats

Coutinho,

Rangel,

Santos

et al. 2024

JASR

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“…circulating sage, and brain, which promote the renewal of cells that have been lost by natural wear, injury, or disease 8 . The present study aimed to evaluate rotator cuff muscle degeneration in sheep and establish an experimental model for the use of autologous stem cells as a treatment option for tendon injuries.…”

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confidence: 99%

Muscle regeneration through therapy with estromal stem cells in injury of infraespinhosus muscle of sheep

et al. 2018

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Coleta de células progenitoras periféricas por aférese automatizada em equino: relato de procedimento

Cited by 2 publications

References 9 publications

Evaluation of Biological Membrane and Stem Cells as Potential Repairs of Tenorraphy in Wistar Rats

Evaluation of Biological Membrane and Stem Cells as Potential Repairs of Tenorraphy in Wistar Rats

Muscle regeneration through therapy with estromal stem cells in injury of infraespinhosus muscle of sheep

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