Collagen in the Developing Larynx

Cheung, David T.; Lian, Grace; Cohen, Seymour R.; Nimni, Marcel E.; Perelman, Natasha; Mahnovski, Vladimir; Carranza, Alfonzo P.

doi:10.1177/000348949210100407

Cited by 11 publications

(9 citation statements)

References 6 publications

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“…The dorsal fiber portion (long arrow) radiates into the aryepiglottic fold. Cohen et al (1992Cohen et al ( , 1993 described differences in the chemical composition of collagen and a lower degree of crosslinking of Type I collagen during the first months of life in healthy individuals. 7).…”

Section: Discussionmentioning

confidence: 99%

Aryepiglottic fold: Normal topography and clinical implications

Reidenbach

1998

Clin. Anat.

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The aryepiglottic folds extend between the arytenoid cartilage and the lateral margin of the epiglottis on each side and constitute the lateral borders of the laryngeal inlet. They are involved in physiologic closure mechanisms of the larynx and in pathologic conditions such as inspiratory stridor. Information on the normal topography of the aryepiglottic folds is poor and controversial. Therefore, this region was reinvestigated in serial whole‐organ sections of 25 plastinated normal adult human larynges. Dorsally, the right and the left aryepiglottic folds are separated by the interarytenoid notch and comprise the corniculate and cuneiform cartilages, as well as numerous groups of mucous glands. Ventrally, the aryepiglottic folds are adjacent to the peri‐epiglottic adipose tissue. Both regions are clearly separated by several layers of transversely oriented collagenous fiber layers. The muscular constituent of the aryepiglottic folds is only poorly developed, and no muscle fibers insert at the epiglottis. A coherent quadrangular membrane representing a ligamentous “skeleton” of the aryepiglottic folds is absent. A conspicuous collagenous fiber layer is found only to strengthen the free dorsal margin of the fold. Both muscular and ligamentous components may render the aryepiglottic folds sufficiently tense as to resist inspiratory inward suction in normal cases. However, pliability must be preserved to guarantee adequate folding in approximation of the aryepiglottic folds during deglutition. Thereby, the posterior part of the laryngeal inlet is closed, whereas the anterior part is probably closed by independent inward bulging of the peri‐epiglottic adipose tissue. Clin. Anat. 11:223–235, 1998. © 1998 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Aryepiglottic fold: Normal topography and clinical implications

Reidenbach

1998

Clin. Anat.

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“…The parameters which define swallowing and its disorders in adults can not be always used in children, because of differences in anatomical structure relations 16 . The pediatric larynx is not simply a miniature of the adult larynx, because there are significant differences in size, its location in relation to the spine, in the make up of cartilage and soft tissue and adaptation to the environment 17,18 . Sound is a mechanical wave which moves through mediums, produced by a vibration source.…”

Section: Introductionmentioning

confidence: 99%

Doppler sonar analysis of swallowing sounds in normal pediatric individuals

Cagliari¹,

Jurkiewicz²,

Santos³

et al. 2009

Braz. j. otorhinolaryngol. (Impr.)

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Among the methods for assessing swallowing sounds -videofluoroscopy modified barium study, fiberoptic swallowing endoscopy, neck auscultation through a microphone, accelerometer and, more recently, the Doppler sonar -we have chosen the latter. Aim: to analyze swallowing sounds by cervical auscultation using Doppler sonar, in a population between 2 and 15 years without oro-pharyngeal dysfunction. Study design: cross-sectional historical cohort. Materials and methods: we investigated 90 individuals in Curitiba (2006Curitiba ( /2007. The population was separated by age into 3 groups: from 2 to 5 years, from 5 to 10 years of age and from 10 to 15 years of age. We obtained the average values for frequency, intensity and swallowing duration for saliva, liquid and pasty foods). Results: objective and measurable data were obtained. Significance related to gender was found in certain age groups and consistencies, under all the studied variables, except swallowing time. Conclusion: neck auscultation using Doppler sonar is a sensitive method to detect swallowing sounds. There was swallowing interference associated with saliva and the other tested food types and with the biological development of the age range being studied. It is an easy to apply method, not expensive and non-invasive.

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“…5,6 Hyaline cartilages undergo changes with time, with progressive enchondral ossification. 7,8 Histopathologic studies demonstrated that the stage of the calcification and ossification is widely affected by age. 9 The order of ossification is affected by the distribution of the mechanical forces applied to the laryngeal cartilages.…”

Section: Discussionmentioning

confidence: 99%