Colonic Perforation at CT Colonography: Assessment of Risk in a Multicenter Large Cohort

Blachar, Arye; Amitai, Maya; Barmeir, Elisha; Peled, Nathan; Goldberg, S. Nahum; Bar‐Ziv, Jacob

doi:10.1148/radiol.2392050287

Cited by 150 publications

(104 citation statements)

References 31 publications

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“…Mortality from colonoscopy has been reported to be as high as 0.07% (1 death every 1500 colonoscopies) [41] though the rate is much lower when colonoscopy is used for screening purposes [42]. Our data on perforations is similar to that reported by the American survey [20,21] and favorably compares with the data from the survey performed in UK and Israel [18,19].…”

Section: Discussionsupporting

confidence: 83%

“…The National Survey of United Kingdom [18] has suggested a perforation rate, for diagnostic studies, of 1 in every 1889 examinations. Similarly, in a large population-based cohort, the incidence of perforations was 0.058%, or one in 1696 studies, with one in 2967 patients requiring surgical intervention [19]. These rates are higher than those reported by the International Working Group on Virtual Colonoscopy [20,21].…”

Section: Introductionmentioning

confidence: 88%

“…However, concerns were raised about recommending CTC as routine screening tool because of potential harm [14,15]. While CTC is widely considered to be much safer than colonoscopy [16][17][18], it is not exempt from potential serious complications, mainly represented by large bowel perforations [18][19][20][21][22]. The National Survey of United Kingdom [18] has suggested a perforation rate, for diagnostic studies, of 1 in every 1889 examinations.…”

Section: Introductionmentioning

confidence: 99%

“…Higher rates of adverse events (AEs) may be a sign of poor quality hospital care and many complications can be prevented if hospitals follow procedures based on the best practice and scientific evidence [20,21]. Ideally, for the standard best practice, continuing training should be required to radiologists or technologists performing CTC examinations at their institutions [19,23,24].…”

Section: Introductionmentioning

confidence: 99%

“…This setting is of interest since previous studies have provided data from specialized centers [19,20] and it remains unknown whether results from these studies can be generalized.…”

Section: Introductionmentioning

confidence: 99%

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Adverse events of computed tomography colonography: An Italian National Survey

Iafrate¹,

Iussich²,

Correale³

et al. 2013

Digestive and Liver Disease

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a b s t r a c tAim: To retrospectively study the frequency and magnitude of complications associated with computed tomography (CT) colonography in clinical practice. Methods: A questionnaire on complications of CT colonography was sent to Italian public radiology departments identified as practicing CT colonography with a reasonable level of training. The frequency of complications and possible risk factors were retrospectively determined. Responses were collated and row frequencies determined. A multivariate analysis of the factors causing adverse events was also performed. Results: 40,121 examinations were performed in13 centers during the study period. No deaths were reported. Bowel perforations occurred in 0.02% (7 exams). All perforations were asymptomatic and occurred in patients undergoing manual insufflation. Five perforations (71%) occurred in procedures performed following a recent colonoscopy. There was no significant difference between perforations associated with rectal balloon (0.017%) and those that were not (0.02%). Complications related to vasovagal reaction (either with or without spasmolytic) occurred in 0.16% (63 exams). All vasovagal reactions resolved in less than 3 h, without any sequelae. Conclusions: Perforation rate at CT colonography in Italy is comparable with elsewhere in the world, occurring regardless of the experience of radiology centers. Although the risk is very small, it may not be negligible when compared with the risk of diagnostic colonoscopy.

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Section: Discussionsupporting

confidence: 83%

Section: Introductionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…This setting is of interest since previous studies have provided data from specialized centers [19,20] and it remains unknown whether results from these studies can be generalized.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Adverse events of computed tomography colonography: An Italian National Survey

Iafrate¹,

Iussich²,

Correale³

et al. 2013

Digestive and Liver Disease

View full text Add to dashboard Cite

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Screening for Thyroid Cancer

Lin

Bowles

Williams

et al. 2017

JAMA

532

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IMPORTANCEThe incidence of detected thyroid cancer cases has been increasing in the United States since 1975. The majority of thyroid cancers are differentiated cancers with excellent prognosis and long-term survival.OBJECTIVE To systematically review the benefits and harms associated with thyroid cancer screening and treatment of early thyroid cancer in asymptomatic adults to inform the US Preventive Services Task Force.

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