Colonic perforation in 91- year- old man with severe Covid-19 infection

Pyar, Khin Phyu; Shan, Min Aung; Hlaing, Soe Win; ., Diwon; Aung, Zarni Htet; Aung, Soe Min; Maung, Nyan Lin; Kyaw, Aung Phyoe

doi:10.17352/jcmbt.000043

Cited by 3 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Khin Phyu et al reported a similar case in a 91-year-old patient who was also managed with right hemicolectomy. However, the patient died two days later [15] . Two studies reported perforation of the right colon in two patients with COVID-19 after being treated with an IL-6 receptor antagonist.…”

Section: Discussionmentioning

confidence: 96%

“…Treatment in these cases must be surgical. Most of the reported cases of colonic perforation in critically ill patients with COVID-19 have been managed with colectomy [14] , [15] , [16] , [17] , [18] . De Nardi et al reported a 53-year-old patient with COVID-19 infection who had a perforation in the ascending colon during his hospitalization.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Large intestinal perforation secondary to COVID-19: A case report

Muñoz¹,

Zapata²,

Gómez³

et al. 2021

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Introduction COVID-19 infection is generally characterized by the presence of respiratory symptoms. However, a small percentage of these patients also have gastrointestinal symptoms and complications that are associated with high morbidity and mortality. Presentation of case A 50-year-old male patient with COVID-19 infection was being treated for COVID-19 and pneumonia in the ICU. He presented with gastrointestinal symptoms, and the computed tomography (CT) scan revealed a hollow viscus perforation. Ultimately, the patient was taken to surgery, where a spontaneous perforation was found in the right colon. The defect was sutured with separate stitches. There were no complications postoperatively. Discussion Although respiratory symptoms are the most common presentation of COVID-19, about 18% of these patients may present with gastrointestinal symptoms. However, an even smaller percentage of critically ill patients may develop serious gastrointestinal complications such as perforation of the large intestine. This unusual complication requires immediate diagnosis and surgical management. Conclusion At the time of the COVID-19 pandemic, physicians must recognize COVID-19 in patients presenting gastrointestinal symptoms. A high degree of clinical suspicion enables timely diagnosis and management, thereby preventing major complications.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Large intestinal perforation secondary to COVID-19: A case report

Muñoz¹,

Zapata²,

Gómez³

et al. 2021

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

show abstract

Severe pseudomembranous colitis in patients with previous coronavirus infection

Тимербулатов¹,

Аитова²,

Grishina³

et al. 2022

Khir. Z. im. N.I. Pirogova

View full text Add to dashboard Cite

COVID-19 and Intestinal Ischemia: A Multicenter Case Series

et al. 2022

View full text Add to dashboard Cite

IntroductionGastrointestinal symptoms are common among COVID-19 patients. Although gastrointestinal involvements are mostly benign, they rarely indicate a severe pathology like intestinal ischemia. The present case series describes 21 patients with bowel ischemia, necrosis, or perforation.MethodsThe present case series was conducted from April 2020 to February 2022 in the surgical wards of two Iranian hospitals. We retrospectively included adult patients with concomitant COVID-19 and intestinal ischemia. Primary outcomes were defined as the length of stay and survival.ResultsTwenty-four patients with a median age of 61.5 years were included in the study. Sixteen (67%) patients were male, and 13 (54%) were without any comorbidities. Macrovascular mesenteric ischemia was not identified in 21 patients (87.5%). Gastrointestinal manifestations appeared on the median of seven days (range 2–21) after the diagnosis of COVID-19, with the most common symptom being abdominal pain. All the patients had a significantly elevated C-Reactive Protein prior to surgery, ranging from 68 to 362. D-dimer was measured in eight patients and was significantly elevated, ranging from 1,878 to over 5,000 ng/mL. One patient was managed conservatively due to a good clinical condition. Except for one patient with angioinvasive mucormycosis and one other with leukocytoclastic vasculitis, pathologic evaluation revealed general features of intestinal necrosis, including ulcer, hemorrhage, necrosis, neutrophilic infiltration (in seven patients), neutrophilic abscess (in four patients), and edema. Bowel necrosis accompanied mortality of 15 (62.5%) patients and a median of 6.5 days of hospital stay.ConclusionIntestinal ischemia in COVID-19 patients is associated with a high mortality rate. Further research is needed to elucidate the dynamics of intestinal ischemia in the setting of COVID-19.

show abstract

Colonic perforation in 91- year- old man with severe Covid-19 infection

Cited by 3 publications

References 11 publications

Large intestinal perforation secondary to COVID-19: A case report

Large intestinal perforation secondary to COVID-19: A case report

Severe pseudomembranous colitis in patients with previous coronavirus infection

COVID-19 and Intestinal Ischemia: A Multicenter Case Series

Contact Info

Product

Resources

About