Color changes in chitosan and poly(allyl amine) films upon metal binding

Schauer, Caroline L.; Chen, Mu‐San; Chatterley, Mandy; Eisemann, Kevin; Welsh, Eric R.; Price, Ronald R.; Schoen, P. E.; Ligler, Frances S.

doi:10.1016/s0040-6090(03)00055-5

Cited by 65 publications

(62 citation statements)

References 28 publications

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“…While in addition to that a sharp band appeared at 1,030 cm -1 in C4S scaffold, which is a characteristic P-O stretching band. The FTIR spectrum is consistent with the result of chitosan fiber modified by phosphate and is attributed to the linkage between phosphate and ammonium ion [48]. So, it is confirmed that the tripolyphosphates are linked with ammonium groups of chitosan in C4S fibers.…”

Section: Resultssupporting

confidence: 85%

Development of chitosan-tripolyphosphate non-woven fibrous scaffolds for tissue engineering application

Pati

Adhikari

Dhara

2012

J Mater Sci: Mater Med

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The fibrous scaffolds are promising for tissue engineering applications because of their close structural resemblance with native extracellular matrix. Additionally, the chemical composition of scaffold is also an important consideration as they have significant influences on modulating cell attachment, morphology and function. In this study, chitosan-tripolyphosphate (TPP) non-woven fibrous scaffolds were prepared through wetspinning process. Interestingly, at physiological pH these scaffolds release phosphate ions, which have significant influences on cellular function. For the first time, cell viability in presence of varying concentration of sodium TPP solution was analyzed and correlated with the phosphate release from the scaffolds during 30 days incubation period. In vitro degradation of the chitosan-TPP scaffolds was higher than chitosan scaffolds, which may be due to decrease in crystallinity as a result of instantaneous ionic cross-linking during fiber formation. The scaffolds with highly interconnected porous structure present a remarkable cytocompatibility for cell growing, and show a great potential for tissue engineering applications.

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Section: Resultssupporting

confidence: 85%

Development of chitosan-tripolyphosphate non-woven fibrous scaffolds for tissue engineering application

Pati

Adhikari

Dhara

2012

J Mater Sci: Mater Med

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“…Diisocyanates, resimene [5], N,N-disuccinimidyl subarate [6], Genipin [7] and glutaraldehyde [8] were the stabilizers for chitosan and chromium [9], aldehydes [10], hexamethylene diisocyanate [11], carbodiimide [12], acylazides [13], citric acid, maleic acid derivatives [14] and various other physical treatments like UV [15] and gamma irradiation [16] were the stabilizers for type-I collagen. All the said exogenous cross-linkers, cross-linked with chitosan or with type-I collagen through; (i) covalent amide/ imine linkage; (ii) metal-protein complex formation (chromium cross-linking with type-I collagen); (iii) H-bond formation (between polyphenolic -OH group with different type of amino acids of type-I collagen molecule and amine group of chitosan) etc.…”

Section: Deacetylated Unit Of Chitosan Acetylated Unit Of Chitosanmentioning

confidence: 99%

Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions

Mitra

Sailakshmi

Gnanamani

et al. 2012

J Mater Sci: Mater Med

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The present study emphasizes the influence of non-covalent interactions on the mechanical and thermal properties of the scaffolds of chitosan/collagen origin. Malonic acid (MA), a bifuncitonal diacid was chosen to offer non-covalent cross-linking. Three dimensional scaffolds was prepared using chitosan at 1.0% (w/v) and MA at 0.2% (w/v), similarly collagen 0.5% (w/v) and MA 0.2% (w/v) and characterized. Results on FT-IR, TGA, DSC, SEM and mechanical properties (tensile strength, stiffness, Young's modulus, etc.) assessment demonstrated the existence of non-covalent interaction between MA and chitosan/collagen, which offered flexibility and high strength to the scaffolds suitable for tissue engineering research. Studies using NIH 3T3 fibroblast cells suggested biocompatibility nature of the scaffolds. Docking simulation study further supports the intermolecular hydrogen bonding interactions between MA and chitosan/collagen.

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“…Cross-linking/stabilizing the collagen/chitosan using exogenous cross-linkers is an effective method to tune the rate of biodegradation and the mechanical property of the scaffolds. Cross-linkers such as resimene, 4 epichlorohydrin, 5 genipin 6 and glutaraldehyde 7 were reported for chitosan. Chromium, 8 aldehydes, 9 hexamethylene diisocyanate, 10 carbodiimide, 11 acylazides 12 citric acid, maleic acid derivatives 13 and various other physical treatments like UV 14 were reported for type-I collagen.…”

Section: Introductionmentioning

confidence: 99%

Studies on Cross-linking of succinic acid with chitosan/collagen

et al. 2013

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The present study summarizes the cross-linking property of succinic acid with chitosan /collagen. In detail, the chemistry behind the cross-linking and the improvement in mechanical and thermal properties of the cross-linked material were discussed with suitable instruments and bioinformatics tools. The concentration of succinic acid with reference to the chosen polymers was optimized. A 3D scaffold prepared using an optimized concentration of succinic acid (0.2% (w/v)) with chitosan (1.0% (w/v)) and similarly with collagen (0.5% (w/v)), was subjected to surface morphology, FT-IR analysis, tensile strength assessment, thermal stability and biocompatibility. Results revealed, cross-linking with succinic acid impart appreciable mechanical strength to the scaffold material. In silico analysis suggested the prevalence of non-covalent interactions, which played a crucial role in improving the mechanical and thermal properties of the cross-linked scaffold. The resultant 3D scaffold may find application as wound dressing material, as an implant in clinical applications and as a tissue engineering material.

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Color changes in chitosan and poly(allyl amine) films upon metal binding

Cited by 65 publications

References 28 publications

Development of chitosan-tripolyphosphate non-woven fibrous scaffolds for tissue engineering application

Development of chitosan-tripolyphosphate non-woven fibrous scaffolds for tissue engineering application

Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions

Studies on Cross-linking of succinic acid with chitosan/collagen

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