Every person has abilities across a multidimensional spectrum; abilities can vary within a person across these dimensions as well as between people along the same dimensions. This paper introduces a preliminary framework for conceptualizing dimensions of ability which we call ability profiles. Our purpose in developing this framework is not to categorize other people, but rather to support research into existing structures that privilege those with strengths in particular dimensions or create a barrier for those with limitations in certain dimensions. Such an analysis is useful for developing inclusive and accessible curricular materials and practices. Through literature reviews, we have developed a framework that describes largegrain dimensions of ability: physical, visual, hearing, cognitive, health, and emotional-behavioral. This paper will introduce ability profiles and the dimensions of ability, describe the relationship between the framework and specific diagnoses, and demonstrate utility of the framework for the physics classroom.