Colorimetric aggregation assay for silver(I) based on the use of aptamer modified gold nanoparticles and C-Ag(I)-C interaction

Ming-luo, Zhou; Tao, Lin; Gan, Xianxue

doi:10.1007/s00604-017-2518-3

Cited by 30 publications

(16 citation statements)

References 33 publications

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“…As a result, the degree of AuNP aggregation is a direct reflection of the target concentration and can be observed by the red to purple-blue color change in the AuNP solution. Based on the similar strategies, the label-free colorimetric detection of various targets, including proteins [77,78,79,80], small organic molecules [81,82,83], and ions, such as silver (I) [84], cadmium (II) [85] and potassium (I) [86], has been explored extensively.…”

Section: Aggregation-based Colorimetric Assaysmentioning

confidence: 99%

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

et al. 2019

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Gold nanoparticles are popularly used in biological and chemical sensors and their applications owing to their fascinating chemical, optical, and catalytic properties. Particularly, the use of gold nanoparticles is widespread in colorimetric assays because of their simple, cost-effective fabrication, and ease of use. More importantly, the gold nanoparticle sensor response is a visual change in color, which allows easy interpretation of results. Therefore, many studies of gold nanoparticle-based colorimetric methods have been reported, and some review articles published over the past years. Most reviews focus exclusively on a single gold nanoparticle-based colorimetric technique for one analyte of interest. In this review, we focus on the current developments in different colorimetric assay designs for the sensing of various chemical and biological samples. We summarize and classify the sensing strategies and mechanism analyses of gold nanoparticle-based detection. Additionally, typical examples of recently developed gold nanoparticle-based colorimetric methods and their applications in the detection of various analytes are presented and discussed comprehensively.

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Section: Aggregation-based Colorimetric Assaysmentioning

confidence: 99%

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

et al. 2019

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“…However, multiple procedures are often needed to obtain sulfhydryl ligands with specific functions, which leads to complicated preparation methods. The commonly used sulfhydryl ligands include thiol [57], thioglycolic acid [58], cysteamine [59], cysteine [60], glutathione [61], protein [62], and acetic acid [63]. Strategies for functionalization of gold nanoparticles (AuNPs) with small molecules were summarized in Figure 3.…”

Section: Functional Modification Of Gold Nanoparticlesmentioning

confidence: 99%

Application of Gold-Nanoparticle Colorimetric Sensing to Rapid Food Safety Screening

Liu

Huang

et al. 2018

Sensors

161

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Due to their unique optical properties, narrow size distributions, and good biological affinity, gold nanoparticles have been widely applied in sensing analysis, catalytic, environmental monitoring, and disease therapy. The color of a gold nanoparticle solution and its maximum characteristic absorption wavelength will change with the particle size and inter-particle spacing. These properties are often used in the detection of hazardous chemicals, such as pesticide residues, heavy metals, banned additives, and biotoxins, in food. Because the gold nanoparticles-colorimetric sensing strategy is simple, quick, and sensitive, this method has extensive applications in real-time on-site monitoring and rapid testing of food quality and safety. Herein, we review the preparation methods, functional modification, photochemical properties, and applications of gold nanoparticle sensors in rapid testing. In addition, we elaborate on the colorimetric sensing mechanisms. Finally, we discuss the advantages and disadvantages of colorimetric sensors based on gold nanoparticles, and directions for future development.

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“…Aptamers are oligonucleotide receptors that can react with the target molecule with high affinity and selectivity. A number of aptamers have been used to detect heavy metal ions [24], such as Hg 2+ [25], Pb 2+ [26], Cd 2+ [27], Ag + [28], and As 3+ [29]. The majority of these solutions are based on a heterogeneous interaction on solid surfaces and therefore require additional equipment to detect induced changes [30].…”

Section: Introductionmentioning

confidence: 99%

Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

et al. 2019

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A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with the target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water.

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Colorimetric aggregation assay for silver(I) based on the use of aptamer modified gold nanoparticles and C-Ag(I)-C interaction

Cited by 30 publications

References 33 publications

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

Application of Gold-Nanoparticle Colorimetric Sensing to Rapid Food Safety Screening

Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

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