Colorimetric and orange light-emitting fluorescent probe for pyrophosphate in water

Recent Development of Chemosensors Based on Cyanine Platforms

“…124-Cu 2+ displayed competitive sensitivity to CN – with a low detection limit of 1.3 μM. The conjugation of hemicyanine and DPA–Zn­(II) was utilized as a pyrophosphate (PPi) fluorescent sensor ( 125-Zn 4+ ) …”

“…124-Cu 2+ displayed competitive sensitivity to CN − with a low detection limit of 1.3 μM. The conjugation of hemicyanine and DPA−Zn(II) was utilized as a pyrophosphate (PPi) fluorescent sensor (125-Zn 4+ ) 169. 125-Zn 4+ achieved fluorescence enhancement (558 nm) toward PPi in water without interference by any of the following species: Zheng and co-workers constructed 126-Zr 4+ for the determination of F − by applying EDTA (ethylenediaminetetraacetic acid)−Zr(IV) complex as the sensing unit.…”

Fluorescent and colorimetric chemosensors for pyrophosphate

“…15). 26 The photophysical properties of 26-2Zn 2+ with PPi were evaluated and a bathochromic shift (27 nm) together with an increase in fluorescence intensity were observed upon the addition of PPi. However, ATP gave a similar, although slightly weaker, fluorescence response.…”

Luminescent probes for the bioimaging of small anionic species in vitro and in vivo

“…40), which readily forms a bis Zn(II) complex as a PPi binding site. 191 In aqueous buffer (pH 7.4) Probe 47-2Zn(II) showed weak emission at 548 nm (l ex = 500 nm, F F = 0.08) and addition of PPi (1.0 equivalent) ''switched on'' emission (F F = 0.10) with a bathochromic shift to 558 nm. While ATP also gave a measurable response, 47-2Zn(II) was used to image PPi uptake in a C2C12 myoblast cell line with a clear increase in intracellular fluorescence observed 30 minutes following addition of 2.5 equivalents of PPi.…”

“…Emission collected at (A, C) blue channel and (B, D) Cy3 channel upon excitation at (A, C) 350 AE 25 nm and (B, D) 543 AE 11 nm. Image reproduced with permission 191.…”