Colorimetric aptasensor for ochratoxin A detection based on enzyme-induced gold nanoparticle aggregation

He, Yue; Tian, Fengyu; Zhou, Jing; Zhao, Qiyang; Fu, Ruijie; Jiao, Bining

doi:10.1016/j.jhazmat.2019.121758

Cited by 95 publications

(36 citation statements)

References 47 publications

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“…The ALP can then hydrolyze ascorbic acid 2-phosphate (AAP) to ascorbic acid (AA), which mediates the reduction of MnO 2 nanosheets to Mn 2+ . These metal cations allow thereby the aggregation of AuNPs and lead to vivid color changes in the sensing system [37]. The dynamic range extends from 6.25 to 750 nM and an improved LOD of 2 ng•mL −1 was recorded.…”

Section: Solution-based Assaysmentioning

confidence: 99%

“…It is worth noting that other detection strategies can implicate NMs as signal mediators in combination with other main colorimetric probes for sensitivity enhancement. As an example, MnO 2 nanosheets can be used in new colorimetric methods based on AuNPs aggregation schemes since MnO 2 nanoflakes can produce abundance metal ions Mn 2+ after decomposition [37], or combined with enzymes to react with catalysis products [34].…”

Section: Nanomaterial-based Probesmentioning

confidence: 99%

“…As an alternative, a combination of enzymatic action and gold nanoparticles aggregation was suggested by He et al [37]. This colorimetric method was developed to detect OTA indirectly via the activity of alkaline phosphatase (ALP) (Figure 3b).…”

Section: Solution-based Assaysmentioning

confidence: 99%

“…(a) Gold nanoparticle-aptamer-based LSPR sensing of ochratoxin a at a widened detection range by double calibration curve method; (b) Colorimetric aptasensor for the ochratoxin A (OTA) assay based on the structure-switching of OTA aptamer coupling with alkaline phosphatase (ALP)-MnO 2 cascade catalytic reaction; (c) Multicolor colorimetric detection of OTA via structure-switching aptamer and enzyme-induced metallization of gold nanorods; (d) pH-Resolved simultaneous detection of four targets based on magnetic separation of two GO platforms with allochroic dyes. Reproduced with permission from[37,40,53,54].…”

mentioning

confidence: 99%

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Advances in Colorimetric Strategies for Mycotoxins Detection: Toward Rapid Industrial Monitoring

Majdinasab

Aissa

Marty

2020

Toxins

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Mycotoxins contamination is a global public health concern. Therefore, highly sensitive and selective techniques are needed for their on-site monitoring. Several approaches are conceivable for mycotoxins analysis, among which colorimetric methods are the most attractive for commercialization purposes thanks to their visual read-out, easy operation, cost-effectiveness, and rapid response. This review covers the latest achievements in the last five years for the development of colorimetric methods specific to mycotoxins analysis, with a particular emphasis on their potential for large-scale applications in food industries. Gathering all types of (bio)receptors, main colorimetric methods are critically discussed, including enzyme-linked assays, lateral flow-assays, microfluidic devices, and homogenous in-solution strategies. This special focus on colorimetry as a versatile transduction method for mycotoxins analysis is comprehensively reviewed for the first time.

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Section: Solution-based Assaysmentioning

confidence: 99%

Section: Nanomaterial-based Probesmentioning

confidence: 99%

Section: Solution-based Assaysmentioning

confidence: 99%

mentioning

confidence: 99%

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Advances in Colorimetric Strategies for Mycotoxins Detection: Toward Rapid Industrial Monitoring

Majdinasab

Aissa

Marty

2020

Toxins

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“…evolution of ligands by exponential enrichment (SELEX) system [11,12]. Additionally, due to its high specificity, compatibility, environment-friendly properties, reliability and ease of synthesis and modification, aptamer opens up novel insights into both qualitative and quantitative determination of organic and inorganic targets such as pesticides [13,14], proteases [15], toxins [16,17], antibiotics [18], and heavy metals [19][20][21][22]. For instance, heavy metals including Pb 2+ , Hg 2+ , and Ag + can be sensed and quantified through specific dimensional structures of aptamer/target complex as "G-quadruplex", "T-Hg 2+ -T", or "C-Ag + -C", respectively [23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Label-Free and Sensitive Determination of Cadmium Ions Using a Ti-Modified Co3O4-Based Electrochemical Aptasensor

et al. 2020

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The current work demonstrates an electrochemical aptasensor for sensitive determination of Cd2+ based on the Ti-modified Co3O4 nanoparticles. In this unlabeled system, Ti-modified Co3O4 nanoparticles act as current signal amplifiers modified on the screen-printed carbon electrode (SPCE) surface, while the derivative aptamer of Cd2+ works as a target recognizer. In addition, the sensing is based on the increase in electrochemical probe thionine current signal due to the binding of aptamer to Cd2+ via specific recognition. In the current study, key parameters, including aptamer concentration, pH, and incubation time were optimized, respectively, to ensure sensing performance. Cyclic voltammetry was used not only to characterize each preparation and optimization step, but also to profile the bindings of aptamer to Cd2+. Under optimal conditions, Cd2+ can be determined in a linear range of 0.20 to 15 ng/mL, with a detection limit of 0.49 ng/mL, significantly below the maximum concentration limit set by the U.S. Environmental Protection Agency. Based on comparative analysis and the results of recovery test with real samples, this simple, label-free but highly selective method has considerable potential and thus can be used as an in-situ environmental monitoring platform for Cd2+ testing.

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Distinguishable Colorimetric Biosensor for Diagnosis of Prostate Cancer Bone Metastases

Li,

Ding,

Zhang

et al. 2023

Advanced Science

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Castration‐resistant prostate cancer (PCa) causes severe bone metastasis (BM), which significantly increases mortality in men with PCa. Imaging tests and radiometric scanning require long analysis times, expensive equipment, specialized personnel, and a slow turnaround. New visualization technologies are expected to solve the above problems. Nonetheless, existing visualization techniques barely meet the urgency for precise diagnosis because the human eyes cannot recognize and capture even slight variations in visual information. By using dye differentiated superposition enhancement colorimetric biosensors, an effective method to diagnose prostate cancer bone metastases (PCa‐BM) with excellent accuracy for naked‐eye quantitative detection of alkaline phosphatase (ALP) is developed. The biomarker ALP specific hydrolytic product ascorbic acid can be detected by rhodamine derivatives (Rd) as gold nanobipyramids (Au NBPs) are deposited and grown. Color‐recombining enhancement effects between Rd and Au NBPs significantly improved abundance. The 150 U L−1 threshold between normal and abnormal can be identified by color. And with color enhancement effect and double signal response, the ALP index is visually measured to diagnose PCa‐BM and provide handy treatment recommendations. Additionally, the proposed colorimetric sensing strategy can be used to diagnose other diseases.

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Colorimetric aptasensor for ochratoxin A detection based on enzyme-induced gold nanoparticle aggregation

Cited by 95 publications

References 47 publications

Advances in Colorimetric Strategies for Mycotoxins Detection: Toward Rapid Industrial Monitoring

Advances in Colorimetric Strategies for Mycotoxins Detection: Toward Rapid Industrial Monitoring

Label-Free and Sensitive Determination of Cadmium Ions Using a Ti-Modified Co3O4-Based Electrochemical Aptasensor

Distinguishable Colorimetric Biosensor for Diagnosis of Prostate Cancer Bone Metastases

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