Combating Antimicrobial Resistance

Threats, Forum on Microbial

doi:10.17226/24914

Cited by 6 publications

(2 citation statements)

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“…Antibiotic prescriptions play a central part in modern medicine as causative therapy for infectious diseases [1,2]. Due to irrational prescribing practices, the rate of multiresistant bacteria has dramatically increased over the last years, and it is more and more challenging to recommend effective empiric antibiotic therapy [3,4]. Despite these circumstances, medical doctors often continue to prescribe antibiotics unreasonably in their daily routine [5,6].…”

Section: Introductionmentioning

confidence: 99%

A clinical decision support system improves antibiotic therapy for upper urinary tract infection in a randomized single-blinded study

Neugebauer

Ebert

Vogelmann

2020

BMC Health Serv Res

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Background: Due to increasing bacterial resistance rates choosing a correct empiric antibiotic therapy is getting more and more complex. Often medical doctors use information tools to make the right treatment choice. Methods: One hundred sixty six participants (77 medical doctors and 89 medical students) were asked to provide a diagnosis and antibiotic therapy in a simple fictive paper case of upper urinary tract infection (UTI) in a randomized single-blinded study. Participants were randomized to one of four information tools they were allowed to use in the study or control: 1. free internet access, 2. pharmaceutical pocket guide, 3. pocket guide antibiotic therapy, 4. clinical decision support system (CDSS), and control (no information tool). The CDSS was designed for the study. The adherence to the national German UTI guideline was evaluated.Results: Only 27.1% (n = 45/166) provided a correct diagnosis of upper UTI and 19.4% (n = 32/166) an antibiotic treatment recommended by national German treatment guidelines indicating their need for information tools. This result was not significantly different between medical doctors and medical students, residents and medical specialists or level of working experience. Using CDSS improved results significantly compared to conventional tools (diagnosis 57.1%; treatment recommendation 40.5%; p < 0,01). Processing time was not different between the use of CDSS and conventional information tools. CDSS users based their decision making on their assigned information tool more than users of conventional tools (73.8% vs. 48.0%; p < 0.01). Using CDSS improved the confidence of participants in their recommendation significantly compared to conventional tools (p < 0.01). Conclusions: Our study suggests that medical professionals require information tools in diagnosing and treating a simple case of upper UTI correctly. CDSS appears to be superior to conventional tools as an information source.

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Section: Introductionmentioning

confidence: 99%

A clinical decision support system improves antibiotic therapy for upper urinary tract infection in a randomized single-blinded study

Neugebauer

Ebert

Vogelmann

2020

BMC Health Serv Res

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“…Устойчивость к фунгицидам -частный случай естественного процесса биологической эволюции организмов, способных адаптироваться к меняющимся условиям внешней среды, что создает проблемы не только для растениеводства. Так, резистентность бактерий и грибов к медицинским препаратам существенно затрудняет лечение больных бактериальными заболеваниями и микозами (8,9). В целом, резистентность патогенных микроорганизмов остается одной из самых острых проблем современности, а снижение риска ее развития у фитопатогенных грибовактуальной задачей сельскохозяйственной науки.…”

Section: развитие резистентности к фунгицидам у фитопатогенных грибовunclassified

Fungicide Resistance of Plant Pathogenic Fungi and Their Chemosensitization as a Tool to Increase Anti-Disease Effects of Triazoles and Strobilurines

Щербакова¹

2019

S-h. biol.

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Antimicrobial Resistance (AMR) Surveillance Under One Health

P¹

2023

Handbook on Antimicrobial Resistance

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Combating Antimicrobial Resistance

Cited by 6 publications

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A clinical decision support system improves antibiotic therapy for upper urinary tract infection in a randomized single-blinded study

A clinical decision support system improves antibiotic therapy for upper urinary tract infection in a randomized single-blinded study

Fungicide Resistance of Plant Pathogenic Fungi and Their Chemosensitization as a Tool to Increase Anti-Disease Effects of Triazoles and Strobilurines

Antimicrobial Resistance (AMR) Surveillance Under One Health

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