Combined Colposcopy, Loop Conization, and Laser Vaporization Reduces Recurrent Abnormal Cytology and Residual Disease in Cervical Dysplasia

Bar‐Am, Amiram; Daniel, Yair; Ron, Ilan G.; Niv, Jacov; Kupferminc, Michael J.; Bornstein, Jacob; Lessing, Joseph B.

doi:10.1006/gyno.2000.5825

Cited by 44 publications

(32 citation statements)

References 17 publications

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“…LEEP can be done easily and rapidly under local anesthesia on an outpatient basis. It is also considered a diagnostic method because it provides histologic findings on the involvement of the surgical margins and the depth of invasion [3,5].…”

Section: Introductionmentioning

confidence: 99%

The “see and treat” strategy for identifying cytologic high‐grade precancerous cervical lesions among low‐income Brazilian women

Nogara

Manfroni²,

Silva

et al. 2012

Intl J Gynecology & Obste

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Section: Introductionmentioning

confidence: 99%

The “see and treat” strategy for identifying cytologic high‐grade precancerous cervical lesions among low‐income Brazilian women

Nogara

Manfroni²,

Silva

et al. 2012

Intl J Gynecology & Obste

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“…The predictive factors of a residual or recurrent lesion have been systematically reviewed in specific studies (3)(4)(5)(6)(7)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). Positive margins are invariably found, but few studies have compared HPV typing before and after treatment (4,12).…”

Section: Predictors Of Recurrencementioning

confidence: 99%

Predictors of recurrence in high-grade cervical lesions and a plan of management

Leguevaque

Motton

Decharme

et al. 2010

European Journal of Surgical Oncology

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“…Because cold knife conization is performed under general anesthesia, and because of the risk of some complications, the traditional surgical technique has been recently replaced by laser conization and LEEP in many Western countries [5][6][7] . Although these methods can provide histologic information including the depth of invasion and the involvement of the surgical margins, several randomized trials have demonstrated that there were no statistically signifi cant differences in cure rates for CIN among these methods [4,8,9] .…”

Section: Discussionmentioning

confidence: 99%

Diagnostic and therapeutic cold knife conization for cervical intraepithelial neoplasia

Dai

Duan

Lin

et al. 2010

Clin. Oncol. Cancer Res.

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OBJECTIVE To evaluate the diagnostic and therapeutic effi cacy of using cold knife conization for cervical intraepithelial neoplasia (CIN). METHODS We retrospectively analyzed 186 cases with CIN diagnosed and treated in our hospital; compared the histologic diagnoses from cervical conization and from colposcopic multiple punch biopsies, and then evaluated their postoperative histologic fi ndings and clinical outcomes. RESULTS Of the 186 cases, there was a correlation in histologic findings between cervical conization and colposcopic multiple punch biopsies in 138 cases (74.2%), and there was no correlation in the other 48 cases (25.8%). Incomplete excision was performed in 8 cases (4.3%), but the failure rate was only 1.1%; the cure rate was 98.9%. Five cases with early invasive cancer were found. Eleven patients underwent subsequent hysterectomy. The main complications associated with conization were hemorrhage and cervical stenosis. Bleeding occurred in 8 (4.3%) of the patients, and cervical stenosis occurred in 3 (1.6%). CONCLUSION Cervical intraepithelial neoplasia was diagnosed more accurately using conization than by colposcopic multiple punch biopsies. Conization can also play an important role in the treatment for CIN. If properly performed, the procedure has a low risk of complications. It can provide an accurate histologic representation of the disease process, and be curative in most cases.

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Combined Colposcopy, Loop Conization, and Laser Vaporization Reduces Recurrent Abnormal Cytology and Residual Disease in Cervical Dysplasia

Cited by 44 publications

References 17 publications

The “see and treat” strategy for identifying cytologic high‐grade precancerous cervical lesions among low‐income Brazilian women

The “see and treat” strategy for identifying cytologic high‐grade precancerous cervical lesions among low‐income Brazilian women

Predictors of recurrence in high-grade cervical lesions and a plan of management

Diagnostic and therapeutic cold knife conization for cervical intraepithelial neoplasia

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