Combined photoacoustic and ultrasound biomicroscopy

Harrison, Tyler; Ranasinghesagara, Janaka; Lu, Huihong; Mathewson, Kory W.; Walsh, Andrew J.; Zemp, Roger J.

doi:10.1364/oe.17.022041

Cited by 86 publications

(60 citation statements)

References 10 publications

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“…In the pulse echo mode, imaging information arises from backscattering of an incident ultrasound wave. To combine both imaging methods, the usual way is to add a pulsed laser source and an illumination system to a conventional ultrasound imaging device [1,3]. A drawback is the finite, often narrow bandwidth of the used piezoelectric transducers, which transmit and receive the ultrasound waves.…”

Section: Introductionmentioning

confidence: 99%

Scanning acoustic-photoacoustic microscopy using axicon transducers

Passler¹,

Nuster²,

Gratt³

et al. 2010

Biomed. Opt. Express

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A dual mode scanning acoustic microscope is investigated, yielding simultaneously images with optical and acoustical contrast. Short laser pulses are used to excite acoustic waves in a sample for the photoacoustic imaging mode. At the same time the pulses irradiate a conical target generating limited diffraction acoustic waves (X-waves) for large depth of field ultrasound imaging. For photoacoustic as well as for ultrasound imaging a focusing, ring shaped detector is applied. First phantom experiments demonstrate the possibility to acquire data for both imaging modes in a single scan, by separating images due to their different time of flight.

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Section: Introductionmentioning

confidence: 99%

Scanning acoustic-photoacoustic microscopy using axicon transducers

Passler¹,

Nuster²,

Gratt³

et al. 2010

Biomed. Opt. Express

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show abstract

“…As PA and US imaging use the same detection instrumentation, they can be easily combined. Several research groups have picked up the idea of combining PA with US imaging by equipping a piezoelectric pulser/receiver device with a laser source [6][7][8][9][10]. These devices are optimized for ultrasound imaging and often do not provide the wide bandwidth that is used in specialized PA imaging devices.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography

Wurzinger

Nuster

Schmitner

et al. 2013

Biomed. Opt. Express

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A tomographic setup that provides the co-registration of photoacoustic (PA) and ultrasound (US) images is presented. For pulseecho US-tomography laser-induced broadband plane ultrasonic waves are produced by illuminating an optically absorbing target with a short near-infrared laser pulse. Part of the same pulse is frequency doubled and used for the generation of PA waves within the object of interest. The laser-generated plane waves are scattered at the imaging object and measured with the same interferometric detector that also acquires the photoacoustic signals. After collection and separation of the data image reconstruction is done using back-projection resulting in threedimensional, co-registered PA and US images. The setup is characterized and the resolution in PA and US mode is estimated to be about 85 µm and 40 µm, respectively. Besides measurements on phantoms the performance is also tested on a biological sample.

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“…Acoustic sensor has been extensively applied to the applications in ultrasound clinic imaging, crack detections of buildings, etc [1][2][3]. The required information can be obtained by measuring the frequencies, power densities and propagation directions of the acoustic waves used basically [4].…”

Section: Introductionmentioning

confidence: 99%

Polarimetric heterodyning fiber laser sensor for directional acoustic signal measurement

Lyu¹,

Wu²,

Tam³

et al. 2013

Opt. Express

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A DBR fiber grating laser acoustic sensor based on polarization beat signal modulation analysis has been demonstrated for directional acoustic signal measurement. The acoustic sensor was fabricated in birefringent erbium-doped fiber, and the influences of external-acoustic pressure on fiber grating laser sensor were analyzed, considering the effect of relative orientation of the acoustic wave on the degrees of birefringence modulation. In experiment, the birefringence in sensing fiber was modulated by ultrasonic pressure. Agreement between theoretical and experimental results was obtained for ultrasound wave propagating from different directions (0-360 degrees in 15 degrees intervals) corresponding to a nonlinearly change in beat frequency modulation rates. The results demonstrate that the DBR fiber grating laser acoustic sensor has an orientation recognizable ability, offering a potential for acoustic vector signal detection.

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Combined photoacoustic and ultrasound biomicroscopy

Cited by 86 publications

References 10 publications

Scanning acoustic-photoacoustic microscopy using axicon transducers

Scanning acoustic-photoacoustic microscopy using axicon transducers

Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography

Polarimetric heterodyning fiber laser sensor for directional acoustic signal measurement

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