Combined portal vein and liver resection for carcinoma of the biliary tract

Nimura, Yuji; Hayakawa, Naokazu; Kamiya, Junichi; Maeda, Satoko; Kondo, Satoshi; Yasui, Akihiro; Shionoya, Shigehiko

doi:10.1002/bjs.1800780629

Cited by 195 publications

(147 citation statements)

References 20 publications

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“…Much controversy exists about the optimum surgical procedure for gallbladder cancer. Recommendations have ranged from simple cholecystectomy to ultraaggressive resections consisting of combined major liver resection and pancreaticoduodenectomy (Nimura et al, 1991). The major problem is that operations required for complete resection of cancer are associated with high morbidity and mortality (Ouchi et al, 1987;Ogura et al, 1991).…”

Section: Discussionmentioning

confidence: 99%

Gallbladder Carcinoma: Analysis of Prognostic Factors in 132 Cases

Xu¹,

Liu²,

Liu³

2012

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 99%

Gallbladder Carcinoma: Analysis of Prognostic Factors in 132 Cases

Xu¹,

Liu²,

Liu³

2012

Asian Pacific Journal of Cancer Prevention

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“…Of the 21 cases treated with palliative operation, the post-surgery mortality was 14% and the mean survival range was only 7 mo. Nimura [30,31] performed a liver and bile duct resection combined with Whipple's operation in five patients with hilar tumors. Two of the five patients died after surgery and the three survivors died 8, 10 and 27 mo later.…”

Section: Discussionmentioning

confidence: 99%

Radiofrequency ablation as a treatment for hilar cholangiocarcinoma

Fan

Liang³

et al. 2008

WJG

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AIM:To explore the role of radio-frequency ablation (RFA) as a treatment for hilar cholangiocarcinoma. M E T H O D S :E l e v e n p a t i e n t s w i t h o b s t r u c t i v e cholestasis underwent Computed Tomography (CT) examination, occupying lesions were observed in the hepatic hilar region in each patient. All lesions were confirmed as cholangioadenocarcinoma by biopsy and were classified as type Ⅲ or Ⅳ by percutaneous transhepatic cholangiography. Patients were treated with multiple electrodes RFA combined with other adjuvant therapy. The survival rate, change of CT attenuation coefficient of the tumor and tumor size were studied in these patients after RFA. RESULTS: In a follow-up CT scan one month after RFA, a size reduction of about 30% was observed in six masses, and two masses were reduced by about 20% in size, three of the eleven masses remained unchanged. In a follow-up CT scan 6 mo after RFA, all the masses were reduced in size (overall 35%), in which the most significant size reduction was 60%. The survival follow-up among these eleven cases was 18 mo in average. Ongoing follow-up showed that the longest survival case was 30 mo and the shortest case was 10 mo. CONCLUSION: RFA is a microinvasive and effective treatment for hilar cholangiocarcinoma.

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“…If the tumor shows the signs of invasion of the perivascular connective tissue, en bloc resection of the right hepatic artery is advocated to obtain a negative surgical margin; therefore, right hemihepatectomy is recommended. If tumor invasion of the portal vein is suspected based on the preoperative imaging or the intraoperative findings, combined resection of the portal vein and reconstruction are the treatment of choice to obtain a negative radical margin [39][40][41] .…”

Section: Vertical Invasion Of the Bile Ductmentioning

confidence: 99%

“…Previously, invasion of a major vessel meant an unresectable tumor. Recent reports have shown improved results when portal vein resection and reconstruction are performed together with major hepatectomy [39][40][41]89] . Neuhaus et al [66] reported a 5-year survival rate of 65% after curative resection of hilar bile duct cancer with portal vein resection and reconstruction.…”

Section: Combined Vascular Resection and Reconstructionmentioning

confidence: 99%

Current surgical treatment for bile duct cancer

Seyama

Makuuchi²

2007

WJG

106

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Since extrahepatic bile duct cancer is difficult to diagnose and to cure, a safe and radical surgical strategy is needed. In this review, the modes of infiltration and spread of extrahepatic bile duct cancer and surgical strategy are discussed. Extended hemihepatectomy, with or without pancreatoduodenectomy (PD), plus extrahepatic bile duct resection and regional lymphadenectomy has recently been recognized as the standard curative treatment for hilar bile duct cancer. On the other hand, PD is the choice of treatment for middle and distal bile duct cancer. Major hepatectomy concomitant with PD (hepatopancreatoduodenectomy) has been applied to selected patients with widespread tumors. Preoperative biliary drainage (BD) followed by portal vein embolization (PVE) enables major hepatectomy in patients with hilar bile duct cancer without mortality. BD should be performed considering the surgical procedure, especially, in patients with separated intrahepatic bile ducts caused by hilar bile duct cancer. Right or left trisectoriectomy are indicated according to the tumor spread and biliary anatomy. As a result, extended radical resection offers a chance for cure of hilar bile duct cancer with improved resectability, curability, and a 5-year survival rate of 40%. A 5-year survival rate has ranged from 24% to 39% after PD for middle and distal bile duct cancer.

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Combined portal vein and liver resection for carcinoma of the biliary tract

Cited by 195 publications

References 20 publications

Gallbladder Carcinoma: Analysis of Prognostic Factors in 132 Cases

Gallbladder Carcinoma: Analysis of Prognostic Factors in 132 Cases

Radiofrequency ablation as a treatment for hilar cholangiocarcinoma

Current surgical treatment for bile duct cancer

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