Combining high power diode lasers using fiber bundles for beam delivery in optoacoustic endoscopy applications

Beam-shaping design for multi-wavelength diode laser stack system coupled into optical fiber for biomedical applications

“…Therefore, in applications focused on biomedical imaging requiring light penetration beyond the optical diffusion limit (up to 1 mm) and high spectral image resolution (<50 µm (Xia et al, 2014), diode laser sources are often selected among the currently available technologies. Hence, they are becoming increasingly popular for biomedical imaging applications, such as photoacoustic tomography (PAT) and endoscopy (PAE) (Xia et al, 2014;Gawali et al, 2016), optical coherence tomography (OCT) (Chen et al, 2017;Suzuki et al, 2019), and diffuse optical imaging (DOI) (Zhang, 2013). The quasi-diffusive and ballistic effects that occur in highly scattering tissues introduce the main limitations in the spatial resolution and depth of imaging applications, requiring a higher contribution of optical power to achieve high penetration depths.…”