Combining non-depolarizing neuromuscular blocking agents: synergism, addition or antagonism?

Lien, Cynthia A.

doi:10.1097/00001503-199908000-00013

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Succinilcolina Versus Rocurônio1

Other Techniques and New Drugs1

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2004

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“…Em 2001, Morris e col. 25 [88][89][90] . Contudo, segundo Lien 91 , apesar dos estudos conduzidos com o objetivo de caracterizar a exata natureza destas interações, outros fatores envolvidos tornam a duração de ação, após emprego da associação de bloqueadores neuromusculares imprevisível. Novos fármacos estão sendo pesquisados, ainda em fase II, isto é, pesquisa com animais.…”

Section: Succinilcolina Versus Rocurôniounclassified

“…The mechanism involved in this result would be an initial pre-synaptic action especially involving rocuronium, resulting in the synergism between it and mivacurium [88][89][90] . However, according to Lien 91 , in spite of studies carried out to characterize the exact nature of such interactions, other factors make duration of action after the association of neuromuscular blockers unpredictable. New drugs are being studied, still in phase II, that is animal research.…”

Section: Other Techniques and New Drugsmentioning

confidence: 99%

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Indução anestésica com a técnica de seqüência rápida

Moro

Módolo²

2004

Rev. Bras. Anestesiol.

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Tracheal intubation after rapid sequence induction of anesthesia is indicated for patients at risk for gastric content aspiration without suspicion of difficult intubation. The adequate indication of the technique, its judicious application and the rational use of available drugs may promote excellent intubation conditions, with fast onset, early return to consciousness and spontaneous breathing in case of tracheal intubation failure.

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Section: Succinilcolina Versus Rocurôniounclassified

Section: Other Techniques and New Drugsmentioning

confidence: 99%