Combining RAFT precipitation polymerization and surface-initiated RAFT polymerization: an efficient approach to prepare hairy particles—supported proline

Abstract

In this paper, a simple and efficient approach for obtaining hairy particles supported proline system is described.

Chiral catalysts immobilized on achiral polymers: effect of the polymer support on the performance of the catalyst

“…308 In this kind of hairy microparticles, the polymer morphology has been demonstrated to be very important to understand not only the catalytic performance but also the potential for efficient reuse. 309 Magnetic supports. In recent years, magnetic nanoparticles (MNPs) have been used extensively as supports for the immobilization of a variety of catalysts including enantioselective catalysts.…”

“…76). 379 The corresponding chiral dendritic ligands (309) were obtained through substitution of the dimethylamino moiety in the original monodentate phosphoramidite by Fréchet-type polyaryl ether dendritic wedges. In this case, the catalytic unit is located at the core and not at the periphery.…”

Polymer ionic liquid network: a highly effective reusable catalyst for one-pot synthesis of heterocyclic compounds

“…L-Proline monomer and cumyl dithiobenzoate (CDB) were prepared according to a previous publication. 2 1 H NMR spectra were obtained using an NMR spectrometer (Bruker 400 MHz). A Thermo FLASH 1112 elemental analyzer was used for elemental analysis.…”

“…MCRs used in combination with asymmetric aldol reactions are powerful tools with which to create a series of heterocycles that have already attracted extensive attention in organic synthesis and drug discovery. 2 Since List et al rst reported proline can efficiently catalyze direct asymmetric aldol reactions, proline and its derivatives have been extensively developed and applied in asymmetric catalytic reactions. [3][4][5][6][7][8][9] However, these methods have some disadvantages, such as limited substrate scope and difficult separation and recycling, that prevent them from further development and application in industry.…”

Temperature-responsive hairy particle-supported proline for direct asymmetric aldol reaction in water

“…[21][22][23] However, the recovery rate was not very ideal. Although, numerous strategies have been used to immobilize chiral catalysts onto solid-supported materials such as polystyrene (beads), dendrimers, ionic liquids and inorganic particles or crosslinked insoluble polymers, [24][25][26][27] they usually show relatively poor catalytic efficiency in water-medium. The intrinsic problem in the heterogeneous catalytic systems is the lower degree of exposure to the reactants.…”