Commentary to the review article: Subedi S, Yu Q, Chen Z, Shi Y. Management of pediatric psoriasis with acitretin: A review. Dermatol Ther. 2018 Jan;31(1)

Barygina, Victoria; Becatti, Matteo; Lotti, Torello; Taddei, Niccolò; Fiorillo, Claudia

doi:10.1111/dth.12700

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…This is in line with previous studies on PedPso treatment, although it is an obsolete strategy in adult patients and, therefore, no longer recommended in guidelines or consensus papers [ 25 , 26 ]. A survey of French paediatricians likewise showed that the use of systemic therapy options is low, with a rate of 4%, and mainly consist of compounds such as steroids or methotrexate [ 27 ], confirming the low rate of 3% reported in our study.…”

Section: Discussionsupporting

confidence: 88%

Management of Paediatric Psoriasis by Paediatricians: A Questionnaire-Based Survey

Pinter

Mielke

Malisiewicz

et al. 2020

Dermatol Ther (Heidelb)

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Introduction Paediatric plaque psoriasis (PedPso) in children and adolescents is often diagnosed and treated for the first time by paediatricians. An early onset of psoriasis is associated with a genetic family burden, higher severity of disease and increased risk of comorbidities, sometimes starting in childhood. However, little information is available on prevalence data and the clinical management of PedPso by paediatricians. Methods A total of 191 questionnaires were sent out to paediatricians regarding their management of PedPso, with a focus on prevalence, diagnosis, initiation of therapies, screening for comorbidities and collaboration with dermatologists. Of these, 95 (49.7%) were returned and evaluated anonymously. Results Only about one-half of the responding paediatricians reported being certain in their diagnosis of PedPso, even though they regularly see moderate-to-severely affected patients. The questionnaire revealed that there are clear differences in the general management of PedPso if the paediatrician is not certain of the diagnosis of psoriasis. Compared to paediatricians certain of their diagnosis, those who are uncertain less frequently perform whole-body inspection, screen for relevant comorbidities, such as psoriasis arthritis, metabolic syndrome or mental disorders, and prescribe the use of topical or systemic therapies. No responding paediatrician reported the use of modern systemic therapies, such as biologicals, even in severely affected children. The majority of respondents rated their cooperation with dermatologists as good. Conclusion The certainty of the diagnosis, the use of system therapies and the screening for comorbidity could improve the care of PedPso through targeted training of paediatricians and intensified interdisciplinary cooperation with dermatologist. Electronic supplementary material The online version of this article (10.1007/s13555-020-00390-y) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 88%

Management of Paediatric Psoriasis by Paediatricians: A Questionnaire-Based Survey

Pinter

Mielke

Malisiewicz

et al. 2020

Dermatol Ther (Heidelb)

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Topical and Oral Therapies for Childhood Atopic Dermatitis and Plaque Psoriasis

et al. 2019

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Background: Treatment of atopic dermatitis and psoriasis in children is difficult due to lack of standardized treatment guidelines and few FDA-approved treatment options. Treatments approved for adults may be used off-label in pediatric patients. Objective: This review evaluates the topical and oral treatment options available, including off-label uses, and provides a basic therapeutic guideline for pediatric atopic dermatitis and psoriasis. Methods: A PubMed review of topical and systemic treatments for pediatric psoriasis and atopic dermatitis with information regarding age, efficacy, dosing, contra-indications, adverse events, and off-label treatments. Results: The search identified seven topical and five systemic treatments that are routinely employed to treat pediatric atopic dermatitis and psoriasis. Limitations: Standardized guidelines regarding treatment choice, dosing, and long-term safety are scarce. Reviews may be subject to ascertainment bias. Conclusions: Current treatment guidelines are based on clinical experience and expert advice with few treatments officially approved for atopic dermatitis and psoriasis in children.

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Commentary to the review article: Subedi S, Yu Q, Chen Z, Shi Y. Management of pediatric psoriasis with acitretin: A review. Dermatol Ther. 2018 Jan;31(1)

Cited by 2 publications

References 14 publications

Management of Paediatric Psoriasis by Paediatricians: A Questionnaire-Based Survey

Management of Paediatric Psoriasis by Paediatricians: A Questionnaire-Based Survey

Topical and Oral Therapies for Childhood Atopic Dermatitis and Plaque Psoriasis

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