2022
DOI: 10.1016/j.jcis.2021.11.145
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Commercial soft contact lenses engineered with zwitterionic silver nanoparticles for effectively treating microbial keratitis

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Cited by 29 publications
(14 citation statements)
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“…1h and i could be correlated with their antibacterial performances against antibiotic-resistant strains. The broad-spectrum antibacterial activity was consistent with our previous research 28,41,[45][46][47] on polycarboxybetaine-modified AgNPs and copper-phenolic networks, which suggested that the strategy of polyzwitterionic functionalization could provide the potential to address the challenge of aggregation-related resistance.…”
Section: Durable Antibacterial Effect and Anti-biofilm Formationsupporting
confidence: 89%
See 1 more Smart Citation
“…1h and i could be correlated with their antibacterial performances against antibiotic-resistant strains. The broad-spectrum antibacterial activity was consistent with our previous research 28,41,[45][46][47] on polycarboxybetaine-modified AgNPs and copper-phenolic networks, which suggested that the strategy of polyzwitterionic functionalization could provide the potential to address the challenge of aggregation-related resistance.…”
Section: Durable Antibacterial Effect and Anti-biofilm Formationsupporting
confidence: 89%
“…3d). As demonstrated in our previous research, 28,41 Ag + released by polyzwitterionic AgNPs provided the major bactericidal effect. The polyzwitterionic surface could hinder the direct endocytosis of AgNPs by bacterial cells.…”
Section: Resultssupporting
confidence: 70%
“…Polymer systems containing silver nanoparticles can be synthesized in situ using the polymer matrix as a reaction medium or ex situ when silver nanoparticles are incorporated into the polymeric matrix already synthetized [ 151 , 152 ]. The latest studies report the use of silver nanoparticles modified with zwitterionic poly (carboxybetaine-co-dopamine methacrylamide) copolymer (PCBDA@AgNPs), which was firmly fixed onto soft contact lenses through the mussel-inspired surface chemistry [ 153 ] or hybrid nanocoatings [ 154 ]. Ye et al described the method of connection between antimicrobial peptides, GL13K and AgNP, to create a hybrid nanocoating on a Ti implant.…”
Section: Improving the Safety Of Biomaterials By Preventing Their Mic...mentioning
confidence: 99%
“…Ophthalmology is also an important application area of biomaterials ( Han H. et al, 2020 ; Wang K. et al, 2021 ). They are widely involved in retinal regeneration ( Abedin Zadeh et al, 2019 ), vitreous replacement ( Wang T. et al, 2021 ), contact lenses ( Xiao et al, 2018 ; Ma et al, 2022 ), and intraocular lenses (IOL) ( Čanović et al, 2019 ). The lens is an important transparent, biconvex-shaped structure for optical functions in the eye.…”
Section: Introductionmentioning
confidence: 99%