Commiphora Berryi Ameliorating Effect on Scopolamine-Induced Memory Impairments in Mice

Abstract

In the present study, we studied the effects of the ethanol extract of Commiphora berryi bark on drug-induced learning and memory-impaired mice using Y-maze task and passive avoidance task. On pretreatment with the ethanol extract of Commiphora berryi at 100mg/Kg p.o significantly ameliorated scopolamine-induced cognitive impairments which were revealed by the reversal in the reduction of spontaneous alteration in the Y -maze task and by significant improvement in latency time in passive avoidance task. This confirms the presence of bioactive phytoconstituents in Commiphora berryi which could be useful to decline the cognitive deficits in memory-impaired mice.