2007
DOI: 10.1016/j.yexcr.2007.05.002
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Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance

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Cited by 84 publications
(84 citation statements)
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“…Simon and colleagues recently confirmed this data by demonstrating that FSH increases the level of expression of Gdnf in the Sertoli cell line TM4 (Simon et al, 2007). In addition, Gdnf production by primary Sertoli cells is also dependent on Fgf2, tumor necrosis factor alpha (Tnfα) and interleukin-1beta (Il-1β) in vitro (Simon et al, 2007). Therefore, Gdnf production by Sertoli cells and SSCs self-renewal are controlled locally and systemically ( Figure 3).…”
Section: Spermatogenesis and The Spermatogonial Stem Cell Nichementioning
confidence: 82%
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“…Simon and colleagues recently confirmed this data by demonstrating that FSH increases the level of expression of Gdnf in the Sertoli cell line TM4 (Simon et al, 2007). In addition, Gdnf production by primary Sertoli cells is also dependent on Fgf2, tumor necrosis factor alpha (Tnfα) and interleukin-1beta (Il-1β) in vitro (Simon et al, 2007). Therefore, Gdnf production by Sertoli cells and SSCs self-renewal are controlled locally and systemically ( Figure 3).…”
Section: Spermatogenesis and The Spermatogonial Stem Cell Nichementioning
confidence: 82%
“…Conversely, primary cultures of Sertoli cells responded to FSH by an increase in Gdnf expression. Simon and colleagues recently confirmed this data by demonstrating that FSH increases the level of expression of Gdnf in the Sertoli cell line TM4 (Simon et al, 2007). In addition, Gdnf production by primary Sertoli cells is also dependent on Fgf2, tumor necrosis factor alpha (Tnfα) and interleukin-1beta (Il-1β) in vitro (Simon et al, 2007).…”
Section: Spermatogenesis and The Spermatogonial Stem Cell Nichementioning
confidence: 87%
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