2013
DOI: 10.1016/j.jbspin.2012.08.004
|View full text |Cite
|
Sign up to set email alerts
|

Common bone turnover markers in rheumatoid arthritis and ankylosing spondylitis: A literature review

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
15
0

Year Published

2014
2014
2020
2020

Publication Types

Select...
8
2

Relationship

0
10

Authors

Journals

citations
Cited by 24 publications
(15 citation statements)
references
References 38 publications
0
15
0
Order By: Relevance
“…The anterior-posterior view of the lumbar spine DXA is very useful in early AS. In the majority of studies, markers of bone resorption (deoxypyridinoline; DPD, type I collagen N-telopeptide; NTX, or type I collagen C-telopeptide; CTX) were increased in AS, although no differences were found in the markers of bone formation (bone-specific alkaline phosphatase; BALP, procollagen type 1 N-terminal peptide; PINP, or osteocalcin) between AS patients and healthy controls [18]. Furthermore, it is important to exclude fractured vertebrae from BMD analysis.…”
Section: Key Pointsmentioning
confidence: 99%
“…The anterior-posterior view of the lumbar spine DXA is very useful in early AS. In the majority of studies, markers of bone resorption (deoxypyridinoline; DPD, type I collagen N-telopeptide; NTX, or type I collagen C-telopeptide; CTX) were increased in AS, although no differences were found in the markers of bone formation (bone-specific alkaline phosphatase; BALP, procollagen type 1 N-terminal peptide; PINP, or osteocalcin) between AS patients and healthy controls [18]. Furthermore, it is important to exclude fractured vertebrae from BMD analysis.…”
Section: Key Pointsmentioning
confidence: 99%
“…These proinflammatory cytokines expressed in the bone microenvironment of rheumatoid arthritis may influence osteoclast differentiation and osteoblast activity. [24,3336] …”
Section: Discussionmentioning
confidence: 99%
“…Several studies [2729] have demonstrated that TNF-α inhibitors and some synthetic DMARDs (such as MTX and sulfasalazine) inhibit the expression of RANKL in RA synoviocytes while augmenting the secretion of OPG in synoviocyte supernatants, and they all inhibited osteoclast formation in vitro. In addition, we cannot forget that the accurate measurement of circulating RANKL is very difficult because of uncertain factors about which forms are the most biologically relevant and the limited sensitivity of available assays [9,13,14]. In this sense, Chan et al showed significant (> 50%) alterations in serum concentration of RANKL after storage for 6 months at both -20°C and -70°C [30].…”
Section: Discussionmentioning
confidence: 99%