Comorbid Irritable Bowel Syndrome in Patients with Generalized Anxiety and Major Depression

Tollefson, Gary D.; Tollefson, Sherrie L.; Pederson, Melissa W.; Luxenberg, Michael G.; Dunsmore, G

doi:10.3109/10401239109147994

Cited by 57 publications

(27 citation statements)

References 15 publications

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“…No specific psychiatric disorder has been linked with IBS, but depression, anxiety, and somatoform disorders have been the most frequently diagnosed conditions [19][20][21]. Reported comorbidity rates between IBS and psychiatric syndromes include major depression at rates of 29% [22] and 27% [23], dysthymia at 60% [24], schizophrenia at 19% [25], and panic disorder at 44% [26]. A recent study suggested a high comorbid rate between IBS and alcohol abuse at 42% [27].…”

Section: Psychiatric Comorbiditymentioning

confidence: 98%

The interface of psychiatry and irritable bowel syndrome

Folks

2004

Curr Psychiatry Rep

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The interface of psychiatry and irritable bowel syndrome (IBS) is well established, with psychiatric comorbidity approaching 20% to 60%. Anxiety disorders, depressive disorders, and somatoform disorders are the more frequently occurring comorbid conditions. Moreover, psychosocial stressors and history of trauma and abuse play a significant role in the onset and perpetuation of IBS symptoms. The psychiatric management of IBS more effectively uses a collaborative approach between a mental health practitioner and a primary care clinician or gastroenterologist. Psychiatric treatment includes the use of pharmacotherapy with antidepressants or anxiolytics, psychotherapy, and attention to psychosocial stressors. Psychiatric interventions have consistently demonstrated effectiveness in reducing IBS symptoms and improvement of patient functioning.

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Section: Psychiatric Comorbiditymentioning

confidence: 98%

The interface of psychiatry and irritable bowel syndrome

Folks

2004

Curr Psychiatry Rep

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“…[1314] Various studies have shown that as many as 30-40% of patient with IBS have co-morbid depression or anxiety disorder. [1516] It has also been reported that patients who come to medical attention tend to have a greater number of symptoms[17] and are more anxious and depressed. [18]…”

Section: Introductionmentioning

confidence: 99%

Prevalence of depression and anxiety in irritable bowel syndrome: A clinic based study from India

Kabra

Nadkarni

2013

Indian J Psychiatry

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Background:Irritable Bowel Syndrome (IBS) is a very common gastrointestinal dysfunction. Despite strong evidence of high prevalence of depression and anxiety in IBS there is very limited research on this in India.Materials and Methods:Cases of IBS and controls with non-ulcerative dyspepsia were recruited from a gastroenterology clinic in Mumbai, India. Presence of anxiety disorder and depression were assessed by using the Hamilton Anxiety rating scale and Hamilton Depression rating scale respectively. Prevalence rates of anxiety and depression were established and Odds Ratio (OR) was calculated to determine the association of depression and anxiety disorders with IBS.Results:In IBS cases, the prevalence of depression and anxiety disorder was 37.1% and 31.4% respectively. In patients with IBS the OR for depression was 6.3 (95% CI 1.6-24.74, P=0.009) and the OR for anxiety disorder was 7.56 (95% CI 1.53-37.29, P=0.01).Conclusion:The prevalence of depression and anxiety disorder in IBS is very high. Therefore, screening of IBS patients for anxiety and depression would facilitate better interventions and consequently better outcomes.

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“…Additional investigations have examined the link between GAD and irritable bowel syndrome (IBS). Approximately 37% of a clinical GAD sample also met diagnostic criteria for IBS (Tollefson, Tollefson, Pederson, Luxenberg, & Dunsmore 1991), and 34% of an IBS patient sample had a lifetime history of GAD (Lydiard 1992). We since found a high degree of comorbidity between GAD and IBS among a general college student sample (Hazlett-Stevens, Craske, Mayer, Chang, & Naliboff 2003;Drews & Hazlett-Stevens, in press).…”

Section: Comorbid Conditionsmentioning

confidence: 98%

Psychological Approaches to Generalized Anxiety Disorder

Hazlett-Stevens¹

2008

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Comorbid Irritable Bowel Syndrome in Patients with Generalized Anxiety and Major Depression

Cited by 57 publications

References 15 publications

The interface of psychiatry and irritable bowel syndrome

The interface of psychiatry and irritable bowel syndrome

Prevalence of depression and anxiety in irritable bowel syndrome: A clinic based study from India

Psychological Approaches to Generalized Anxiety Disorder

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