Comorbidities in Patients With Ischemic Heart Disease: Gender Differences

Sumin, А. N.; Korok, E. V.; Щеглова, А. В.; Barbarash, O. L.

doi:10.20996/1819-6446-2017-13-5-622-629

Cited by 10 publications

(6 citation statements)

References 20 publications

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“…for angioplasty and stenting of coronary arteries, had standard indications (a burdened anamnesis, a functional class of the underlying disease) for performing a surgery for myocardial revascularization. The incidence of cardiovascular and major cerebrovascular pathologies was typical for the patients with stable angina pectoris [14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Life Quality Assessment of Patients With Stable Coronary Artery Disease After Myocardial Revascularization

Наркевич

Немятых

Ковалева

et al. 2021

Farm. farmakol. (Pâtigorsk)

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The aim of this study is to assess the life quality of patients with stable coronary artery disease after angioplasty and stenting of coronary arteries at the post-hospital stage.Materials and methods. Methods of the sociological analysis (questionnaire surveys) and methods of mathematical statistics (descriptive statistics, time series method, factor and variance analyses) were used at different stages of the prospective observational study. The research materials were as follows:1458 electronic patient records with a stable coronary heart disease (SCHD) after angioplasty and stenting of coronary arteries (ASCA); 620 questionnaires filled in by patients before the surgery, 1, 6, 12 months after discharge. The statistical analysis was performed using the IBM SPSS Statistics software.Results. The results of a comprehensive survey make it possible for us to assert that during the studied period, stable good healths of cardiac surgery patients with ASCA were maintained. Within the framework of the EQ-5D-5L questionnaire, it was revealed that more than 50% of patients have no physiological problems. The results of the SAQ analysis demonstrate that 58% of the patients feel better, and more than 34% of the patients do not have shortness of breath 1 year after the surgery. A statistically significant improvement in their healths was established according to a visual analogue scale relatively to the annual observation mark (62.82 ± 20.95), which corresponds to the high results assessment of the medical technology use. At the same time, 53% of the patients notify that the treatment results meet their own expectations.Conclusion. The proposed calculation of the integrated index of patients’ treatment efficiency demonstrated by the patients with stable coronary heart disease after angioplasty and stenting of the coronary arteries is based on the results of the factor analysis. This calculation can be used to assess the efficiency of pharmacotherapy in the framework of a value-oriented approach to the treatment of a number of other pathologies.

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Section: Discussionmentioning

confidence: 99%

Life Quality Assessment of Patients With Stable Coronary Artery Disease After Myocardial Revascularization

Наркевич

Немятых

Ковалева

et al. 2021

Farm. farmakol. (Pâtigorsk)

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“…Шальновой, С.А. Бойцова и других авторских коллективов [2,8,10,11]. При этом широкое назначение свободных комбинаций лекарственных препаратов кардиологами обусловлено не предпочтениями врачей, не отсутствием компетенций специалистов, а требованием федерального законодательства о выписке Antihypertensive Therapy with Ramipril and Amlodipine Fixed Combination Антигипертензивная терапия фиксированной комбинацией рамиприла и амлодипина лекарственных средств по международным непатентованным наименованиям [22].…”

Section: Discussionunclassified

“…При этом среди пациентов, перенесших острый коронарный синдром (ОКС) и/или стентирование инфаркт-зависимой коронарной артерии, распространенность АГ составляет более 80% [2]. В течение, по меньшей мере, года после перенесенного ОКС пациенты с АГ обречены на полифармацию, что затрудняет проведение адекватной лекарственной терапии [3].…”

Section: Aimunclassified

Antihypertensive Efficacy of Fixed Combination of Amlodipine and Ramipril in Patients with Arterial Hypertension and Very High Cardiovascular Risk

Korennova

Podolnaya

Prihodko

et al. 2019

Racionalʹnaâ farmakoterapiâ v kardiologii

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Aim. To evaluate the antihypertensive efficacy and tolerability of a fixed combination of amlodipine and ramipril in hypertensive patients with very high cardiovascular risk. Material and methods. A retrospective cohort study of real clinical practice of prescribing antihypertensive drugs according to 255 medical records of outpatient hypertensive patients with a history of acute coronary syndrome (ACS) and coronary artery stenting was performed in the first part. An open observational study was performed in the second part. 69 people older than 18 years with a history of ACS and coronary artery stenting, without reaching the target blood pressure (BP) level while using free combinations of antihypertensive drugs and with indications for a fixed combination of ramipril and amlodipine were included into the study. Analysis of self-monitoring of BP, office BP, daily BP monitoring (ABPM) and patients’ adherence to treatment (Morisky-Green test) initially, after 4 and after 12 weeks of taking the fixed combination of ramipril and amlodipine was performed to assess the clinical efficacy of the studied drug. Results. It was found that 42.0% of patients did not follow the recommendations for regular intake of antihypertensive drugs. So, hypertension of all patients regarded as false-refractory, which was the basis for the prescription of the fixed combination of ramipril and amlodipine in accordance with clinical guidelines for the diagnosis and treatment of hypertension. After 4 weeks of therapy, there was significant decrease in office BP with the achievement and preservation of the target level by the 12th week, normalization to the 12th week of day and night BP variability in 54.9% of patients. 78.0% of patients followed medical recommendations for regular administration of antihypertensive drugs, none of the patients had adverse events. Conclusion. The use of fixed combinations of drugs, in particular, amlodipine and ramipril as a part of multicomponent therapy in hypertensive patients with very high cardiovascular risk, led to the achievement of target BP by the 4th week of therapy and stable preservation of antihypertensive effect in 12 weeks of treatment as well as gradual normalization of day and night BP variability in more than half of patients. Fixed combination of ramipril and amlodipine allowed to improve adherence of patients to cardiovascular diseases.

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“…According to the latest guidelines by the European Society of Cardiology regarding treatment of patients after MI with ST segment elevation, prescription of beta-adrenergic blocking agents (BB) is recommended for all patients with reduced ejection fraction (EF) and hearth insuffi ciency symptoms (class of recommendations 1, level A). The recommendations also denote the necessity of BB prescription to less serious patients after primary PCI if there are no contraindications nor symptoms of acute ventricular failure [40,41]. Angiotensin-converting enzyme inhibitor as well as sartans are recommended for all patients with IHD and such states as arterial hypertension, DM, CHF or chronic kidney disease (class of recommendations 1, level A) [2].…”

Section: Modifi Able Risks Before Elective Pci: Prognostic Signifi Camentioning

confidence: 99%

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

et al. 2019

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The article is a topical literature review of the place of percutaneous coronary interventions in the structure of elective revascularisation procedures, preoperative preparation of patients with stable ischaemic heart disease before percutaneous coronary intervention, the prospects of the technique, taking into account the latest advances in intervention cardiology (intravascular methods for assessing the hemodynamic significance of stenosis, drug eluting stents). Modern data of the early and long-term results of percutaneous coronary intervention are presented, the predictable potentially modifiable risks of adverse events are described, and ways to correct them are discussed. The results of randomised studies comparing the effectiveness of different approaches for managing patients with stable coronary heart disease (medical therapy, percutaneous coronary intervention) are presented, and prospects for using new drugs to improve the early and late outcomes of endovascular revascularisation are discussed.

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Comorbidities in Patients With Ischemic Heart Disease: Gender Differences

Cited by 10 publications

References 20 publications

Life Quality Assessment of Patients With Stable Coronary Artery Disease After Myocardial Revascularization

Life Quality Assessment of Patients With Stable Coronary Artery Disease After Myocardial Revascularization

Antihypertensive Efficacy of Fixed Combination of Amlodipine and Ramipril in Patients with Arterial Hypertension and Very High Cardiovascular Risk

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

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