Comorbidity and Mortality in COPD-Related Hospitalizations in the United States, 1979 to 2001

Holguín, Fernando; Folch, Erik; Redd, Stephen C.; Mannino, David M.

doi:10.1378/chest.128.4.2005

Cited by 340 publications

(275 citation statements)

References 15 publications

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“…Of these, about 36 million discharges (79%) occurred with COPD as a secondary diagnosis, and 9.8 million (20.8%) occurred with COPD as the primary diagnosis. 114 In 2008, the estimated direct economic cost of COPD and asthma was $53.7 billion. These costs included prescription medicines ($20.4 billion), visits to outpatient clinics or office-based providers ($13.2 billion), hospital inpatient stays ($13.1 billion), home healthcare ($4.0 billion), and emergency department visits ($3.1 billion).…”

Section: Copd Costmentioning

confidence: 99%

The Empirical Foundations of Telemedicine Interventions for Chronic Disease Management

Bashshur

Shannon

Smith

et al. 2014

Telemedicine and e-Health

309

210

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The telemedicine intervention in chronic disease management promises to involve patients in their own care, provides continuous monitoring by their healthcare providers, identifies early symptoms, and responds promptly to exacerbations in their illnesses. This review set out to establish the evidence from the available literature on the impact of telemedicine for the management of three chronic diseases: congestive heart failure, stroke, and chronic obstructive pulmonary disease. By design, the review focuses on a limited set of representative chronic diseases because of their current and increasing importance relative to their prevalence, associated morbidity, mortality, and cost. Furthermore, these three diseases are amenable to timely interventions and secondary prevention through telemonitoring. The preponderance of evidence from studies using rigorous research methods points to beneficial results from telemonitoring in its various manifestations, albeit with a few exceptions. Generally, the benefits include reductions in use of service: hospital admissions/readmissions, length of hospital stay, and emergency department visits typically declined. It is important that there often were reductions in mortality. Few studies reported neutral or mixed findings.

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Section: Copd Costmentioning

confidence: 99%

The Empirical Foundations of Telemedicine Interventions for Chronic Disease Management

Bashshur

Shannon

Smith

et al. 2014

Telemedicine and e-Health

309

210

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“…The presence of COPD has an adverse impact on hospital admission rate and subsequent inpatient mortality in those with IHD [27], as well as survival following angiography [28].…”

Section: Ischemic Heart Diseasementioning

confidence: 99%

Extrapulmonary comorbidities in chronic obstructive pulmonary disease: state of the art

Patel

Hurst

2011

Expert Review of Respiratory Medicine

137

108

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“…An important factor in both the prognosis and functional capabilities of COPD patients is the role of comorbid disease [4,5]. There are several important steps in evaluating comorbid disease in COPD.…”

mentioning

confidence: 99%

“…The first is to define the diseases that occur with an increasing frequency in subjects with evidence of COPD, and the second is to determine the effect that comorbid disease has on health-related outcomes. The disease processes most closely linked to COPD include lung cancer [6], depression [7], congestive heart failure [5] and ischaemic heart disease [5]. However, there are several other diseases potentially linked to respiratory disease or its treatment with a weaker association, i.e.…”

mentioning

confidence: 99%

Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD

Mannino

Thorn²,

Swensen³

et al. 2008

Eur Respir J

998

717

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Chronic obstructive pulmonary disease (COPD) is associated with important chronic comorbid diseases, including cardiovascular disease, diabetes and hypertension.The present study analysed data from 20,296 subjects aged o45 yrs at baseline in the Atherosclerosis Risk in Communities Study (ARIC) and the Cardiovascular Health Study (CHS). The sample was stratified based on baseline lung function data, according to modified Global Initiative for Obstructive Lung Disease (GOLD) criteria. Comorbid disease at baseline and death and hospitalisations over a 5-yr follow-up were then searched for.Lung function impairment was found to be associated with more comorbid disease. In logistic regression models adjusting for age, sex, race, smoking, body mass index and education, subjects with GOLD stage 3 or 4 COPD had a higher prevalence of diabetes (odds ratio (OR) 1.5, 95% confidence interval (CI) 1.1-1.9), hypertension (OR 1.6, 95% CI 1.3-1.9) and cardiovascular disease (OR 2.4, 95% CI 1.9-3.0). Comorbid disease was associated with a higher risk of hospitalisation and mortality that was worse in people with impaired lung function.Lung function impairment is associated with a higher risk of comorbid disease, which contributes to a higher risk of adverse outcomes of mortality and hospitalisations.

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Comorbidity and Mortality in COPD-Related Hospitalizations in the United States, 1979 to 2001

Cited by 340 publications

References 15 publications

The Empirical Foundations of Telemedicine Interventions for Chronic Disease Management

The Empirical Foundations of Telemedicine Interventions for Chronic Disease Management

Extrapulmonary comorbidities in chronic obstructive pulmonary disease: state of the art

Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD

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