Comparação do ultrassom pulsado e contínuo no reparo tendíneo de ratos

Abstract

RESUMO | No tratamento de lesões tendíneas, o uso do ultrassom surge como possibilidade terapêutica, apesar de lacunas sobre seus efeitos clínicos. O objetivo foi avaliar dois protocolos de ultrassom terapêutico sobre dor e edema após trauma tendíneo. Vinte e um ratos Wistar foram submetidos a trauma no tendão calcâneo e divididos em três grupos: sham (GS); ultrassom contínuo (GUC); e ultrassom pulsado (GUP). O trauma ocorreu sobre a face lateral do tendão calcâneo direito, com energia de 0,40 J. A dor foi avaliada pelo teste de incapacidade funcional e o edema, pelo diâmetro laterolateral. Foram realizadas avaliações previamente à lesão; após 1 hora da indução da lesão; após o 1º tratamento; 2, 8 e 24 horas após lesão; e após o 5º dia. O tratamento ocorreu em 5 dias, com transdutor de 1 MHz, durante 3 minutos, sobre o local do trauma, com dose de 0,4 W/cm 2 SATA. Os resultados da incapacidade funcional para GS mostraram aumento da nocicepção. Para GUC houve aumento ao comparar a avaliação 1 (AV1) com as avaliações 2 (AV2), 3 (AV3) e 4 (AV4); ao comparar AV2 com as avaliações 5 (AV5) e 6 (AV6) houve diminuição de valores. Para GUP houve aumento ao comparar AV1 com AV2 e AV3, mas ao comparar AV2 com as seguintes, houve diminuição significativa a partir de AV4. Para o edema, os grupos tratados produziram aumento inicial, com redução nas últimas avaliações. O ultrassom terapêutico produziu diminuição de dor e edema, mais precocemente para a forma pulsada.Descritores | tendão do calcâneo; ultrassom; dor; regeneração.ABSTRACT | In tendon injuries treatment, the use of ultrasound appears as a therapeutic option, despite the lack of their clinical effects. The aim was to evaluate two therapeutic ultrasound protocols, continuous or pulsed, on the pain and swelling after tendinous trauma. Twenty-one Wistar rats were subjected to traumatic injury in the tendon and divided in three groups: sham (GS), continuous ultrasound (GUC), and pulsed ultrasound (GUP). The injury occurred on right Achilles tendon lateral aspect, with energy of 0.40 J. The pain was assessed by the functional disability test and edema by latero-lateral diameter. The evaluations were performed before the injury; after 1 hour of the lesion induction; after the 1st treatment; 2, 8 and 24 hours after injury; and after the 5th day. The treatment was made for 5 consecutive days, with transductor of 1 MHz, for 3 minutes on the trauma site, with a dose of 0.4 W/cm 2 SATA. The results of functional disability for GS showed increased nociception. For GUC, there was increased when comparing evaluation 1 (EV1) with evaluations 2 (EV2), 3 (EV3) and 4 (EV4); comparing EV2 to evaluations 5 (AV5) and 6 (AV6), there was decreased values. To GUP there was increased when comparing EV1 with EV2 and EV3, but when comparing EV2 with the following, there was a significant decrease starting from EV4. Edema, treatment groups produced an initial increase with a reduction in recent evaluations. The therapeutic ultrasound produced pain and edema reduction in rats with tendon traum...

Comparison of continuous and pulsed ultrasound therapy in knee hyperalgesia of Wistar rats

“…This is different from what has been observed by a study with tendon trauma in rats, where there has been increased edema evaluated 2 and 8h after trauma, with significant decreases 24 hours later. They also mention that nociception evaluated by clinching time, has shown hypernociception decrease 8 hours after for GUP and just 24 hours after for GUC 14 . Although being different times, pattern was similar to our study where the two therapies used have produced nociceptive threshold decrease 20 minutes after for pulsed and 60 minutes after for continuous ultrasound.…”

Therapeutic ultrasound ameliorates hyperalgesia and edema on CFA-induced persistent inflammatory response in mice

“…In the study conducted by Bertolini et al, 20 the authors used the same parameters used in this study, considering the intensity of 0.4 W.cm −2 and a five-day treatment frequency. The authors observed that US treatment decreases the pain and acute edema in animals with calcaneus tendon injuries.…”

“…The therapeutic ultrasound device produced by the Ibramed® Brazilian Industry of medical equipment (Amparo, São Paulo/Brasil) was applied to the mice's left hind paw following the US continuous parameters (Frequency: 1 MHz; ERA: 1 cm 2 ; Duty cycle: 100%; Intensity: 0.4 W.cm −2 ; BNR: 8:1; Time: 3 min) and US Pulsed (Frequency: 1 MHz; ERA: 1 cm 2 ; Duty cycle: 20%; Pulse frequency: 100 Hz; Intensity: 2 W.cm −2 ; SATA: 0.4 W.cm −2 ; BNR: 8:1; Time: 3 min). 20 , 21 , 22 , 23 Both pulsed and continuous US groups were submitted to the underwater technique in the plantar region of the left hind paw, with a distance of 0.5 to 1.0 cm between the paw and the US transducer. The placebo group received an application simulation with the equipment switched off.…”

Efeitos do ultrassom terapêutico no ingurgitamento mamário: estudo piloto

“…De acordo com Bertolini 23 , os efeitos terapêuticos do ultrassom não térmico advêm da cavitação estável e do micro fluxo acústico, que podem alterar a estrutura, permeabilidade e função da membrana celular, estimulando a rápida resolução do processo inflamatório, o reparo e regeneração tecidual, e assim produzir efeitos analgésicos e de redução do edema.…”