Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Abstract

Atrial and ventricular function are closely related. Right atrial strain is currently being studied for validation. The purpose of our research is to evaluate its behavior in patients with pulmonary hypertension and compare it with healthy adults, with the hypothesis that right atrial strain would be lower in the first group. Methods: This is an observational, cross-sectional study. Only subjects with secondary pulmonary hypertension were included in the patient group. Subjects underwent systematic echocardiography with equipment from Philips (Epic 7), acquiring routine 2D images in standard and modified 4 chamber view, for assessment of right atrial function and estimated pulmonary arterial systolic pressure in both groups. The respective post-processing analysis software used was QLAB 9 (Cardiac motion quantification (CMQ)). Results: A total of 60 subjects, 30 in each group, were included. The mean age was 78 years in the pulmonary hypertension group (60% male), and 26 years in the healthy subjects (16% males). The mean pulmonary systolic pressure in the patient group was 60 mmHg (p <0.0001). Right atrial mean global longitudinal strain was 17.8% in patient group vs 44% in the control group, p <0.0001. Conclusions: The longitudinal global strain of the right atrium is significantly lower in patients with pulmonary hypertension compared against healthy subjects. The reservoir phase of the atrial cycle had the biggest difference in deformation between both groups.