The aim of this study is to analyze the factorial structure of the Multidimensional Body–Self Relations Questionnaire—Appearance Scales (MBSRQ-AS) to determine the adjustment of the study structure proposed in the Spanish short version in a young, non-clinical Chilean population and to evaluate the possible influence of sex, age, and BMI on body image measurement. The sample consisted of 614 Chilean youth (259 male and 355 female) between 15 and 28 years old (M = 18.81; SE = 2.46), from the Metropolitan Region, and four regions of the coast and south-central zone of the country. The average Body Mass Index (BMI) was 22.5 kg/m2 (SD = 3.16). The model fit was evaluated by confirmatory factor analysis (WLSMV) using the following: a model with a single general factor, a model with the five factors of the original version, a five-factor ESEM model, and a MIMIC model analyzed including sex, age, and BMI. The results show that the MIMIC sex, age, and BMI model presents an acceptable fit, observing that four factors, Appearance Orientation (AO), Body Areas Satisfaction (BAS), Overweight Preoccupation (OP), and Self-Classification Weight (SCW), are affected significantly for the sex variable, one for age, Appearance Evaluation (AE), and four for BMI (AE, BAS, OP, and SCW). In conclusion, MBSRQ-AS replicates the five-dimensional structure in a non-clinical sample of young Chileans; however, their scores are not invariant as they depend on sex, age, and BMI.