2023
DOI: 10.3390/covid3040034
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Comparative Analysis and Classification of SARS-CoV-2 Spike Protein Structures in PDB

Abstract: The Spike (S) protein of the SARS-CoV-2 virus that causes the COVID-19 disease is considered the most important target for vaccine, drug and therapeutic research as it attaches and binds to the ACE2 receptor of the host cells and allows the entry of this virus. Analysis and classification of newly determined S protein structures for SARS-CoV-2 are critical to properly understand their functional, evolutionary and architectural relatedness to already known protein structures. In this paper, first, the comparati… Show more

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