Comparative analysis of intensity modulation inverse planning modules of three commercial treatment planning systems applied to head and neck tumour model

Outcomes of Postoperative Simultaneous Modulated Accelerated Radiotherapy for Head-and-Neck Squamous Cell Carcinoma

“…Several investigators have reported significant dosimetric improvements in SMART-IMRT compared to sequential IMRT (12)(13)(14). To date, the clinical outcome of SMART on HNSCC have been very promising based on the available published results (10).…”

Hyperfractionated Radiotherapy in Locally Advanced Nasopharyngeal Cancer

“…More rigorous treatment strategies are clearly needed for advanced tumors. Numerous authors report a better target/normal tissue dose distribution using intensity-modulated radiation therapy (IMRT), stereotactic irradiation (SRT), or two-step intensity-modulated arch therapy (two-step IMAT) [4,5,16,20,24,41,47,58,64,70]. These modalities can allow for optimization of the dose distribution and administration of higher cumulative irradiation doses (e.g., 81 Gy).…”

Three-dimensional conformal vs. intensity-modulated radiotherapy in head-and-neck cancer patients: comparative analysis of dosimetric and technical parameters

“…In our objectives, these parameters had the first priority. Dose plan normalization was set at the mean dose to the PTV rather than at the ICRU point (1,3). Targets treated with IMRT were covered entirely by modulated fields without any matching with conventional beams (e.g.…”

“…As a further development of a previous phase carried out, at the planning level, for various anatomic sites (1)(2)(3)(4), this report will focus on the main technical and dosimetric issues to take into consideration in an early phase of the IMRT clinical implementation, with particular attention to headand-neck cancer treatment.…”