Comparative Analysis of Mg-Dependent and Mg-Independent HCO3 − ATPases

Abstract

The comparative analysis between two enzymes, Mg-dependent and Mg-independent HCO3(-) ATPases, were studied in synaptosomal and microsomal membrane fractions of albino rat brain, using the method of kinetic analysis of the multi-sited enzyme systems. Therefore, it can be inferred that Mg-dependent HCO3(-) ATPase belongs to the group of "P-type" transporting ATPases. Mg-independent HCO3(-) ATPase with its kinetic properties may be attributed to the group of "Ecto" ATPases.