Comparative analysis of the efficacy and accuracy of magnetic resonance imaging (MRI) and contrast-enhanced CT for residual and new lesions after transcatheter arterial chemoembolization (TACE) in patients with primary liver cancer

Abstract

Background: The purpose of this study was to investigate the efficacy and accuracy of magnetic resonance imaging (MRI) and contrast-enhanced computed tomography (CECT) for residual and new lesions after transcatheter arterial chemoembolization (TACE) in patients with primary liver cancer (PHC).Methods: Seventy-two PHC patients admitted to Linyi Central Hospital from May 2018 to May 2020 were selected as the study subjects, with a total of 92 lesions. All patients were treated with TACE, and were followed up at 6 months postoperatively. In addition, all patients underwent digital subtraction angiography (DSA), and with DSA results serving as the gold standard for diagnosis, the efficacy and accuracy of MRI and CECT for residual and new lesions after TACE in PHC patients were evaluated.Results: There were no significant differences in the specificity between the two diagnostic methods (P>0.05), and the diagnostic accuracy and sensitivity of MRI were markedly higher than those of CECT (P<0.05). The number of residual and new lesions diagnosed by MRI was notably higher than that by multislice spiral computed tomography (MSCT) (P<0.05), and the detection rate of residual and new lesions after TACE in PHC patients with different types of iodized oil deposition by MRI was significantly higher than that by CECT (P<0.05). Also, the number of postoperative tumor capsules diagnosed by MRI was considerably higher than that by CECT (P<0.05). There were no significant differences between the two diagnostic methods in the score of residual enhancement appearances in the arterial phase after surgery (P>0.05). Furthermore, there were no notable differences between the two diagnostic methods in the diagnosis of portal vein tumorous emboli and the source of blood supply to lesions after surgery (P>0.05). Conclusions:The diagnostic accuracy and sensitivity of MRI for residual and new lesions after TACE in PHC patients were higher than those of CECT. However, these two diagnostic methods were similar in diagnosing portal vein tumorous emboli, the source of blood supply to lesions, and the score of residual enhancement appearances in the arterial phase after surgery.

Clinical Significance of Liver MR Imaging

“…9). 43 Stereotactic body radiation therapy (SBRT) is one of the treatment options for HCC; however, it is not mentioned in the JSH guideline. Although LI-RADS treatment response criteria can be applied after SBRT, it should be noted that there are posttreatment changes specific to SBRT.…”

Evaluation of the efficacy of transcatheter arterial embolization combined with apatinib on rabbit VX2 liver tumors by intravoxel incoherent motion diffusion-weighted MR imaging

“…Most patients with liver cancer need multiple sessions of TAE, therefore, accurate and repeated postoperative evaluation of the tumor focus is a key factor for the timely detection of survival and recurrence of cancer ( 6 , 7 ). Intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) can distinguish the diffusion of water molecules in tissue lesion areas and microperfusion of the local capillary network, and estimate the Apparent Diffusion Coefficient (ADC), True Diffusion Coefficient (D), Pseudodiffusion Coefficient (D*) and Perfusion Fraction ( f ), which can be used to quantitatively distinguish surviving and necrotic tumor tissues at an early stage by multiple parameters ( 8 , 9 ).…”